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      Biomechanical performance evaluation of a modified proximal humerus locking plate for distal humerus shaft fracture using finite element analysis

      research-article
      1 , 2 , 3 , 1 , 2 , 3 , , 4 ,
      Scientific Reports
      Nature Publishing Group UK
      Trauma, Biomedical engineering

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          Abstract

          The extra-articular distal humerus plate (EADHP) has been widely used for surgical treatment of distal humerus shaft fracture (DHSF). However, the surgical approach, fixation methods, and implant positions of the EADHP remain controversial owing to iatrogenic radial nerve injury and complaints such as skin irritation related to the plate. Anterior plating with a modified (upside-down application) proximal humerus locking plate (PHILOS) has been proposed as an alternative, However, research on its biomechanical performance remain insufficient and were mostly based on retrospective studies. This study quantitatively compared and evaluated the biomechanical performance between posterior plating with the EADHP and anterior plating with a modified PHILOS using finite element analysis (FEA). The FEA simulation results that both the EADHP and PHILOS had adequate biomechanical performance and stability under axial, bending, and varus force load conditions. The PHILOS has a fixed stability comparable to that of the EADHP, and fixation was achieved using only four locking screws within a fixed range of 30 mm just above the olecranon fossa. The results show that the PHILOS could be an option for the fixation of a DHSF when considering the dissection range and complaints (e.g. skin irritation) associated with the EADHP.

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          Most cited references29

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          Extra-articular distal-third diaphyseal fractures of the humerus. A comparison of functional bracing and plate fixation.

          There are strong advocates for both operative and nonoperative treatment of distal-third diaphyseal fractures of the humerus, but there are few comparative data. We performed a retrospective comparison of these two treatment methods. Fifty-one consecutive patients with a closed, extra-articular fracture of the distal one-third of the humeral diaphysis were identified from an orthopaedic trauma database. Forty patients were followed for at least six months or until healing of the fracture. Eleven patients were excluded because of inadequate follow-up. Nineteen patients had been managed with plate-and-screw fixation, and twenty-one had been managed with functional bracing. Among the operatively treated patients, one had loss of fixation, one had a postoperative infection, and one required tendon transfers for the treatment of a preoperative radial nerve palsy that did not resolve. Three new postoperative radial nerve palsies developed, and one had not resolved when the patient was last evaluated, three months after surgery. All operatively treated fractures healed with 30 degrees of malalignment in any plane. Two patients had development of skin breakdown during treatment and completed treatment in a sling. Two patients lost >/=20 degrees of elbow or shoulder motion. For extra-articular distal-third diaphyseal humeral fractures, operative treatment achieves more predictable alignment and potentially quicker return of function but risks iatrogenic nerve injury and infection and the need for reoperation. Functional bracing can be associated with skin problems and varying degrees of angular deformity, but function and range of motion are usually excellent.
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            Nonunions of the humerus.

            Humerus fractures comprise 5% to 8% of all fractures. Nonunions are uncommon, but when they occur, they present a challenge to the orthopaedic surgeon and often are debilitating to patients. There are risk factors that may predispose patients to nonunion. Many methods of treating these nonunions have been described with varying degrees of success. We review the literature concerning the treatment of proximal, midshaft, and distal humeral nonunions and describe our treatment protocol based on the literature.
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              Plate selection for fixation of extra-articular distal humerus fractures: A biomechanical comparison of three different implants

              Operative fixation of extra-articular distal humerus using a single posterolateral column plate has been described but the biomechanical properties or limits of this technique is undefined. The purpose of this study was to evaluate the mechanical properties of distal humerus fracture fixation using three standard fixation constructs. Two equal groups were created from forty sawbones humeri. Osteotomies were created at 80mm or 50mm from the tip of the trochlea. In the proximal osteotomy group, sawbones were fixed with an 8-hole 3.5mm LCP or with a 6-hole posterolateral plate. In the distal group, sawbones were fixed with 9-hole medial and lateral 3.5mm distal humerus plates and ten sawbones were fixed with a 6-hole posterolateral plate. Biomechanical testing was performed using a servohydraulic testing machine. Testing in extension as well as internal and external rotation was performed. Destructive testing was also performed with failure being defined as hardware pullout, sawbone failure or cortical contact at the osteotomy. In the proximal osteotomy group, the average bending stiffness and torsional stiffness was significantly greater with the posterolateral plate than with the 3.5mm LCP. In the distal osteotomy group, the average bending stiffness and torsional stiffness was significantly greater with the posterolateral plate than the 3.5mm LCP. In extension testing, the yield strength was significantly greater with the posterolateral plate in the proximal osteotomy specimens, and the dual plating construct in the distal osteotomy specimens. The yield strength of specimens in axial torsion was significantly greater with the posterolateral plate in the proximal osteotomy specimens, and the dual plating construct in the distal osteotomy specimens. Limited biomechanical data to support the use of a pre-contoured posterolateral distal humerus LCP for fixation of extra-articular distal humerus exists. We have found that this implant provided significantly greater bending stiffness, torsional stiffness, and yield strength than a single 3.5mm LCP plate for osteotomies created 80mm from the trochlea. At the more distal osteotomy, dual plating was biomechanically superior. Our results suggest that single posterolateral column fixation of extra-articular humerus fractures is appropriate for more proximal fractures but that dual plate fixation is superior for more distal fractures.
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                Author and article information

                Contributors
                kimkg@gachon.ac.kr
                dryoonyc@gachon.ac.kr
                Journal
                Sci Rep
                Sci Rep
                Scientific Reports
                Nature Publishing Group UK (London )
                2045-2322
                27 September 2023
                27 September 2023
                2023
                : 13
                : 16250
                Affiliations
                [1 ]Department of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences and Technology (GAIHST), Gachon University, ( https://ror.org/03ryywt80) Incheon, 21999 Republic of Korea
                [2 ]Department of Biomedical Engineering, College of Medicine, Gachon University, ( https://ror.org/03ryywt80) Incheon, 21565 Republic of Korea
                [3 ]Medical Devices R&D Center, Gachon University Gil Medical Center, ( https://ror.org/005nteb15) Incheon, 21565 Republic of Korea
                [4 ]Orthopedic Trauma Division, Trauma Center, Gachon University Gil Medical Center, ( https://ror.org/005nteb15) Incheon, 21565 Republic of Korea
                Article
                43183
                10.1038/s41598-023-43183-x
                10533898
                37758839
                c2617f03-f4bd-4c65-9197-adb9942f6ee4
                © Springer Nature Limited 2023

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 1 June 2023
                : 20 September 2023
                Funding
                Funded by: the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT)
                Award ID: NRF-2021R1G1A1094042
                Funded by: FundRef http://dx.doi.org/10.13039/501100002631, Gachon University;
                Award ID: GCU-202205980001
                Funded by: the Gachon Program
                Award ID: GCU-202106290001
                Categories
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                © Springer Nature Limited 2023

                Uncategorized
                trauma,biomedical engineering
                Uncategorized
                trauma, biomedical engineering

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