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      A qualitative systematic review of factors influencing parents’ vaccination decision-making in the United Kingdom

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          Abstract

          Background

          High uptake of vaccinations is crucial for disease prevention. Although overall uptake of childhood immunisations is high in the United Kingdom (UK), pockets of lower uptake remain. Novel systematic methods have not been employed when reviewing the qualitative literature examining parents’ vaccination decisions.

          Aims

          We aimed to conduct a qualitative systematic review of studies in the UK to understand factors influencing parental decisions to vaccinate a child.

          Methods

          On 12/2/14 we searched PsycINFO, MEDLINE, CINAHL plus, Embase, Social Policy and Practice and Web of Science for studies using qualitative methods and reporting reasons why parents in the UK had or had not immunised their child. Participant quotes and authors’ interpretations of qualitative data were extracted from the results of articles. Thematic synthesis was used to develop higher-order themes (conducted in 2015).

          Results

          34 papers were included. Two types of decision-making had been adopted: non-deliberative and deliberative. With non-deliberative decisions parents felt they had no choice, were happy to comply and/or relied on social norms. Deliberative decisions involved weighing up the risks and benefits, considering others’ advice/experiences and social judgement. Emotions affected deliberative decision-making. Trust in information and vaccine stakeholders was integral to all decision-making. Practical issues affected those who intended to vaccinate.

          Conclusions

          Parents adopted two different approaches to decision-making about childhood vaccinations. By understanding more about the mechanisms underpinning parents’ vaccination behaviour, in collaboration with vaccine stakeholders, we can better design interventions to enhance informed uptake.

          Highlights

          • This qualitative systematic review identified 2 types of vaccine decision-making.

          • Some parents’ decision-making was non-deliberative, while others’ was deliberative.

          • Findings will help design interventions to enhanced informed uptake of vaccines.

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          Most cited references31

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          Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.

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            Vaccine hesitancy: Definition, scope and determinants.

            The SAGE Working Group on Vaccine Hesitancy concluded that vaccine hesitancy refers to delay in acceptance or refusal of vaccination despite availability of vaccination services. Vaccine hesitancy is complex and context specific, varying across time, place and vaccines. It is influenced by factors such as complacency, convenience and confidence. The Working Group retained the term 'vaccine' rather than 'vaccination' hesitancy, although the latter more correctly implies the broader range of immunization concerns, as vaccine hesitancy is the more commonly used term. While high levels of hesitancy lead to low vaccine demand, low levels of hesitancy do not necessarily mean high vaccine demand. The Vaccine Hesitancy Determinants Matrix displays the factors influencing the behavioral decision to accept, delay or reject some or all vaccines under three categories: contextual, individual and group, and vaccine/vaccination-specific influences.
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              Methods for the thematic synthesis of qualitative research in systematic reviews

              Background There is a growing recognition of the value of synthesising qualitative research in the evidence base in order to facilitate effective and appropriate health care. In response to this, methods for undertaking these syntheses are currently being developed. Thematic analysis is a method that is often used to analyse data in primary qualitative research. This paper reports on the use of this type of analysis in systematic reviews to bring together and integrate the findings of multiple qualitative studies. Methods We describe thematic synthesis, outline several steps for its conduct and illustrate the process and outcome of this approach using a completed review of health promotion research. Thematic synthesis has three stages: the coding of text 'line-by-line'; the development of 'descriptive themes'; and the generation of 'analytical themes'. While the development of descriptive themes remains 'close' to the primary studies, the analytical themes represent a stage of interpretation whereby the reviewers 'go beyond' the primary studies and generate new interpretive constructs, explanations or hypotheses. The use of computer software can facilitate this method of synthesis; detailed guidance is given on how this can be achieved. Results We used thematic synthesis to combine the studies of children's views and identified key themes to explore in the intervention studies. Most interventions were based in school and often combined learning about health benefits with 'hands-on' experience. The studies of children's views suggested that fruit and vegetables should be treated in different ways, and that messages should not focus on health warnings. Interventions that were in line with these suggestions tended to be more effective. Thematic synthesis enabled us to stay 'close' to the results of the primary studies, synthesising them in a transparent way, and facilitating the explicit production of new concepts and hypotheses. Conclusion We compare thematic synthesis to other methods for the synthesis of qualitative research, discussing issues of context and rigour. Thematic synthesis is presented as a tried and tested method that preserves an explicit and transparent link between conclusions and the text of primary studies; as such it preserves principles that have traditionally been important to systematic reviewing.
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                Author and article information

                Contributors
                Journal
                SSM Popul Health
                SSM Popul Health
                Ssm - Population Health
                Elsevier Ltd
                2352-8273
                1 December 2016
                December 2016
                : 2
                : 603-612
                Affiliations
                [a ]Health Behaviour Research Centre, UCL, Gower Street, London WC1E 6BT, United Kingdom
                [b ]Institute of Child Health, UCL, 30 Guilford Street, London WC1N 1EH, United Kingdom
                [c ]Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, United Kingdom
                Author notes
                [* ]Corresponding author. Alice.Forster@ 123456ucl.ac.uk
                Article
                S2352-8273(16)30047-7
                10.1016/j.ssmph.2016.07.005
                5165048
                28018959
                bfe94aac-72a8-43c1-b4b6-f269753902fc
                © 2016 The Authors

                This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

                History
                : 3 April 2016
                : 20 June 2016
                : 22 July 2016
                Categories
                Review Article

                thematic synthesis,vaccination,parents,patient acceptance of health care

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