Molecular Subtyping and Surveillance of Resistance Genes In Treponema pallidum DNA From Patients With Secondary and Latent Syphilis in Hunan, China.

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Abstract

Over the past decade, the incidence of syphilis and widespread macrolide resistance in its etiological agent, Treponema pallidum subsp. pallidum, have become a major health concern across countries, including China. Regional trends in subtypes and antibiotic resistance can be monitored effectively by molecular surveillance programs. In this study, whole blood samples were used to assess circulating T. pallidum strains collected from various regions of Hunan, China, between 2013 and 2015.

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Journal

Journal ID (iso-abbrev): Sex Transm Dis

Title: Sexually transmitted diseases

Publisher: Ovid Technologies (Wolters Kluwer Health)

ISSN (Electronic): 1537-4521

ISSN (Print): 0148-5717

Publication date (Electronic): May 2016

Volume: 43

Issue: 5

Affiliations

[1 ] From the *Pathogenic Biology Institute, Medical College, University of South China; †Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study; ‡Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control; §Department of Clinical Laboratory, The Second Affiliated Hospital of University of South China; ¶Department of Clinical Laboratory, The First Affiliated Hospital of University of South China; and **Department of Experimental Zoology, Medical College, University of South China, Hengyang, China.

Article

Publisher Item ID: 00007435-201605000-00008

DOI: 10.1097/OLQ.0000000000000445

PubMed ID: 27100768

SO-VID: bdccbcc8-9998-459a-8ef5-ec7f68f66fd7

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