Cardiac electrophysiological substrate underlying the ECG phenotype and electrogram abnormalities in Brugada syndrome patients.

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Abstract

Brugada syndrome (BrS) is a highly arrhythmogenic cardiac disorder, associated with an increased incidence of sudden death. Its arrhythmogenic substrate in the intact human heart remains ill-defined.

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Author and article information

Journal

Journal ID (iso-abbrev): Circulation

Title: Circulation

ISSN (Electronic): 1524-4539

ISSN (Print): 0009-7322

Publication date (Electronic): Jun 2 2015

Volume: 131

Issue: 22

Affiliations

[1 ] From Cardiac Bioelectricity and Arrhythmia Center (J.Z., P.C., J.S., D.C., M.F., Y.R.) and Department of Biomedical Engineering (J.Z., Y.R.), Washington University, St. Louis, MO; Bordeaux University Hospital, LIRYC Institute, Pessac, France (F.S., M. Hocini, M. Haïssaguerre); School of Medicine, University of Wisconsin, Madison (K.H.); Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD (T.O.); CardioInsight Technologies, Cleveland, OH (M. Strom); School of Medicine, Washington University, St. Louis, MO (P.C., J.S., D.C., M.F., Y.R.); and School of Medicine, University of California, San Francisco (M. Scheinman).

[2 ] From Cardiac Bioelectricity and Arrhythmia Center (J.Z., P.C., J.S., D.C., M.F., Y.R.) and Department of Biomedical Engineering (J.Z., Y.R.), Washington University, St. Louis, MO; Bordeaux University Hospital, LIRYC Institute, Pessac, France (F.S., M. Hocini, M. Haïssaguerre); School of Medicine, University of Wisconsin, Madison (K.H.); Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD (T.O.); CardioInsight Technologies, Cleveland, OH (M. Strom); School of Medicine, Washington University, St. Louis, MO (P.C., J.S., D.C., M.F., Y.R.); and School of Medicine, University of California, San Francisco (M. Scheinman). rudy@wustl.edu.

Article

Publisher Item ID: CIRCULATIONAHA.114.013698 Mid ID: NIHMS675325

DOI: 10.1161/CIRCULATIONAHA.114.013698

PubMed ID: 25810336

SO-VID: bbf9243c-8d89-4868-9dcd-2af585fcf9b6

History

Keywords: Brugada syndrome,electrocardiography,electrophysiology

Data availability:

Keywords: Brugada syndrome, electrocardiography, electrophysiology

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