MiRNA-30e mediated cardioprotection of ACE2 in rats with Doxorubicin-induced heart failure through inhibiting cardiomyocytes autophagy.

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Abstract

miRNAs are a class of small non-coding RNAs that has been proved to be involved in cardioprotection. The present study was to detect role of miR-30e in cardiac-protective action of ACE2 (angiotensin-converting enzyme 2).

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Journal

Journal ID (iso-abbrev): Life Sci.

Title: Life sciences

Publisher: Elsevier BV

ISSN (Electronic): 1879-0631

ISSN (Print): 0024-3205

Publication date (Electronic): Jan 15 2017

Volume: 169

Affiliations

[1 ] Department of Cardiology, the First People's Hospital of Hangzhou, Hangzhou 310006, China.

[2 ] Department of Cardiology, the First People's Hospital of Hangzhou, Hangzhou 310006, China. Electronic address: c_junzhu@163.com.

Article

Publisher Item ID: S0024-3205(16)30552-5

DOI: 10.1016/j.lfs.2016.09.006

PubMed ID: 27633839

SO-VID: b586f404-5686-4f27-981f-3ae0841a6d01

History

Keywords: LC3-II/I,rhACE2,Beclin-1,Caspase-3,Autophagy

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Keywords: LC3-II/I, rhACE2, Beclin-1, Caspase-3, Autophagy

MiRNA-30e mediated cardioprotection of ACE2 in rats with Doxorubicin-induced heart failure through inhibiting cardiomyocytes autophagy.

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