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SEAVIEW and PHYLO_WIN: two graphic tools for sequence alignment and molecular phylogeny
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Abstract
<p class="first" id="d9202895e63">SEAVIEW and PHYLO_WIN are two graphic tools for
X Windows-Unix computers dedicated
to sequence alignment and molecular phylogenetics. SEAVIEW is a sequence alignment
editor allowing manual or automatic alignment through an interface with CLUSTALW program.
Alignment of large sequences with extensive length differences is made easier by a
dot-plot-based routine. The PHYLO_WIN program allows phylogenetic tree building according
to most usual methods (neighbor joining with numerous distance estimates, maximum
parsimony, maximum likelihood), and a bootstrap analysis with any of them. Reconstructed
trees can be drawn, edited, printed, stored, evaluated according to numerous criteria.
Taxonomic species groups and sets of conserved regions can be defined by mouse and
stored into sequence files, thus avoiding multiple data files. Both tools are entirely
mouse driven. On-line help makes them easy to use. They are freely available by anonymous
ftp at biom3.univ-lyon1.fr/pub/ mol_phylogeny or http:@acnuc.univ-lyon1.fr/, or by
e-mail to galtier@biomserv.univ-lyon1.fr.
</p>