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Immunogenicity, safety, and tolerability of a recombinant measles-virus-based chikungunya vaccine: a randomised, double-blind, placebo-controlled, active-comparator, first-in-man trial
Katrin Ramsauer ,
Michael Schwameis ,
Christa Firbas ,
Matthias Müllner ,
Robert J Putnak ,
Stephen J Thomas ,
Philippe Desprès ,
Erich Tauber ,
Bernd Jilma ,
Frederic Tangy
May 2015
May 2015
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Abstract
Chikungunya is an emerging arthropod-borne disease that has spread from tropical endemic
areas to more temperate climates of the USA and Europe. However, no specific treatment
or preventive measure is yet available. We aimed to investigate the immunogenicity
and safety of a live recombinant measles-virus-based chikungunya vaccine.