The epidemiology of drug-resistant epilepsy: A systematic review and meta-analysis.

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Abstract

The definition of drug-resistant epilepsy (DRE) affects case identification and treatment, and impacts prevalence or incidence estimates and health burden estimation in epidemiology. The objective of this systematic review is to evaluate the consistency between definitions of DRE in the literature and the official definition in the International League Against Epilepsy (ILAE) guidelines, and to estimate the incidence, prevalence, and risk factors for DRE.

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Author and article information

Journal

Journal ID (iso-abbrev): Epilepsia

Title: Epilepsia

Publisher: Wiley

ISSN (Electronic): 1528-1167

ISSN (Print): 0013-9580

Publication date (Electronic): December 2018

Volume: 59

Issue: 12

Affiliations

[1 ] UCB Pharma, Raleigh, North Carolina.

[2 ] Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

[3 ] UCB Pharma, Brussels, Belgium.

[4 ] UCB Pharma, Monheim, Germany.

[5 ] Refractory Epilepsy Unit, Neurology Service, Hospital Universitario y Politécnico La Fe, Valencia, Spain.

Article

DOI: 10.1111/epi.14596

PubMed ID: 30426482

SO-VID: b1cc671b-9bc3-4e57-a5ea-c5ed6f69e707

History

Keywords: risk,drug resistant,epidemiology,epilepsy,frequency,review

Data availability:

Keywords: risk, drug resistant, epidemiology, epilepsy, frequency, review

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