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      Methods and Mechanisms of Photonic Disinfection

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          Abstract

          Healthcare-associated infections (HAIs) are a growing social and economic problem in the United States. A HAI is an infection that develops as a result of medical care and is typically contracted in a hospital, outpatient surgery center, nursing home, rehabilitation facility, or while receiving wound care services. One new tool to fight the increasing threat of HAIs is photonic disinfection (optical light-based disinfection). Photonic disinfection of air, surfaces, and liquids has witnessed rapid adoption within many industries (e.g., drinking water purification, wastewater treatment, indoor air purification) over the past 20 years. More recently, light-based disinfection technologies have started to make their way into hospitals, clinics, and medical centers to aid in the disinfection of air and surfaces. Two photonic disinfection methods of interest are the use of ultraviolet-C wavelengths (200 nm to 280 nm) and blue wavelengths (400 nm to 420 nm). These wavelengths of interest have been proven to be effective disinfection tools and should be put into use to augment traditional infection-prevention techniques.

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          Most cited references11

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          Inactivation kinetics and efficiencies of UV-LEDs against Pseudomonas aeruginosa , Legionella pneumophila , and surrogate microorganisms

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            Economic burden of healthcare-associated infections: an American perspective.

            Annually, approximately 2 million patients suffer with healthcare-associated infections (HAIs) in the USA, and nearly 90,000 are estimated to die. The overall direct cost of HAIs to hospitals ranges from US$28 billion to 45 billion. While the range is wide, HAIs are clearly expensive. In addition, most HAIs are thought to be preventable; however, published guidelines are not congruent. Important policy changes include mandating hospitals to publically report HAI rates and a federal pay-for-performance measure that will no longer allow Medicare to pay more for patients with HAIs. Further rigorous economic evaluations of specific interventions, as well as on evaluations of the policies, are required.
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              Reactivation of ultra-violet-inactivated bacteriophage by visible light.

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                Author and article information

                Contributors
                Journal
                J Res Natl Inst Stand Technol
                J Res Natl Inst Stand Technol
                JRES
                Journal of Research of the National Institute of Standards and Technology
                [Gaithersburg, MD] : U.S. Dept. of Commerce, National Institute of Standards and Technology
                1044-677X
                2165-7254
                2021
                20 August 2021
                : 126
                : 126016
                Affiliations
                [1 ]Light Sources Inc., Orange, CT 06477, USA
                Article
                126016
                10.6028/jres.126.016
                9681197
                36475077
                af9c253a-fcd4-490e-9fc5-d5db516db187
                Copyright @ 2021

                The Journal of Research of the National Institute of Standards and Technology is a publication of the U.S. Government. The papers are in the public domain and are not subject to copyright in the United States. Articles from J Res may contain photographs or illustrations copyrighted by other commercial organizations or individuals that may not be used without obtaining prior approval from the holder of the copyright.

                History
                : 21 April 2021
                Funding
                Funded by: National Institute of Standards and Technology
                Award ID: 9999-NIST
                Categories
                Article

                blue light,healthcare-associated infections,ultraviolet disinfection,ultraviolet-c radiation

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