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      Prediction of G-protein-coupled receptor classes in low homology using Chou's pseudo amino acid composition with approximate entropy and hydrophobicity patterns.

      Protein and Peptide Letters
      Algorithms, Amino Acid Sequence, Amino Acids, analysis, Animals, Cattle, Computational Biology, methods, Data Interpretation, Statistical, Databases, Protein, Entropy, Hydrophobic and Hydrophilic Interactions, Molecular Sequence Data, Receptors, G-Protein-Coupled, chemistry, classification, Rhodopsin

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          Abstract

          We use approximate entropy and hydrophobicity patterns to predict G-protein-coupled receptors. Adaboost classifier is adopted as the prediction engine. A low homology dataset is used to validate the proposed method. Compared with the results reported, the successful rate is encouraging. The source code is written by Matlab.

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