In vitro extracellular matrix model to evaluate stroma cell response to transvaginal mesh.

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Abstract

The use of surgical mesh for female pelvic floor reconstruction has increased in recent years. However, there is paucity of information about the biological responses of host stroma cells to different meshes. This study was aimed to establish an in vitro experimental model to study the micro-environment of extracellular matrix (ECM) with embedded mesh and the stroma cell behaviors to different synthetic meshes.

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Author and article information

Journal

Journal ID (iso-abbrev): Neurourol. Urodyn.

Title: Neurourology and urodynamics

Publisher: Wiley

ISSN (Electronic): 1520-6777

ISSN (Print): 0733-2467

Publication date (Electronic): Apr 2014

Volume: 33

Issue: 4

Affiliations

[1 ] Division of Urogynecology and Pelvic Floor Reconstruction, Department of Obstetrics and Gynecology, Chi Mei Foundation Hospital, Tainan, Taiwan; Center of General Education, Chia Nan University of Pharmacy and Science, Tainan, Taiwan.