Nonexpanded primary lung and bone marrow-derived mesenchymal cells promote the engraftment of umbilical cord blood-derived CD34(+) cells in NOD/SCID mice.

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Abstract

Previously, we have found that human culture-expanded fetal lung-derived mesenchymal stem cells (MSC) promote the engraftment of umbilical cord blood (UCB)-derived CD34((+)) cells. The high frequency of MSC in fetal lung allowed us to study whether this represented a biological feature of these cells or a property that was acquired during expansion in culture.

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Journal

Journal ID (iso-abbrev): Exp Hematol

Title: Experimental hematology

Publisher: Elsevier BV

ISSN: 0301-472X

ISSN (Print): 0301-472X

Publication date (Electronic): Oct 2003

Volume: 31

Issue: 10

Affiliations

[1 ] Departments of Obstetrics and Hematology, Leiden University Medical Center, Leiden, The Netherlands.

Article

Publisher Item ID: S0301472X03002029

DOI: 10.1016/s0301-472x(03)00202-9

PubMed ID: 14550803

SO-VID: ab1d5956-aa4c-4517-9faa-9cddbc885098

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