Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis.

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Abstract

Inflammation may play an important role in cancer progression, and a high neutrophil-to-lymphocyte ratio (NLR) has been reported to be a poor prognostic indicator in several malignancies. Here we quantify the prognostic impact of this biomarker and assess its consistency in solid tumors.

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Journal

Journal ID (iso-abbrev): J Natl Cancer Inst

Title: Journal of the National Cancer Institute

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 1460-2105

ISSN (Print): 0027-8874

Publication date (Electronic): Jun 2014

Volume: 106

Issue: 6

Affiliations

[1 ] Affiliations of authors: Divisions of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Department of Medicine, University of Toronto, Toronto, Canada (AJT, MGM, FEV-B, PA, RL-A, JJK, IFT, EA); Department of Medical Oncology, Institute of Oncology Ljubljana, Slovenia (BS); Medical Oncology University Hospital, Albacete, Spain (AO); University of Alabama, Birmingham Comprehensive Cancer Center, Birmingham, AL (GS); Department of Medical Oncology, Royal Melbourne Hospital, Melbourne, Australia (BT).

[2 ] Affiliations of authors: Divisions of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Department of Medicine, University of Toronto, Toronto, Canada (AJT, MGM, FEV-B, PA, RL-A, JJK, IFT, EA); Department of Medical Oncology, Institute of Oncology Ljubljana, Slovenia (BS); Medical Oncology University Hospital, Albacete, Spain (AO); University of Alabama, Birmingham Comprehensive Cancer Center, Birmingham, AL (GS); Department of Medical Oncology, Royal Melbourne Hospital, Melbourne, Australia (BT). eitan.amir@uhn.ca.

Article

Publisher Item ID: dju124

DOI: 10.1093/jnci/dju124

PubMed ID: 24875653

SO-VID: a9d091a6-14ba-4b60-995e-44ceaa5ebc4c

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