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      Pain sensitization in people with knee osteoarthritis: a systematic review and meta-analysis.

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          Abstract

          Emerging evidence suggests that pain sensitization plays an important role in pain associated with knee osteoarthritis (OA). This systematic review and meta-analysis examined the evidence for pain sensitization in people with knee OA and the relationship between pain sensitization and symptom severity.

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          Author and article information

          Journal
          Osteoarthr. Cartil.
          Osteoarthritis and cartilage
          1522-9653
          1063-4584
          Jul 2015
          : 23
          : 7
          Affiliations
          [1 ] School of Public Health, Physiotherapy and Population Science, University College Dublin, Dublin, Ireland. Electronic address: caitriona.fingleton@ucdconnect.ie.
          [2 ] St. Vincent's University Hospital, Dublin, Ireland.
          [3 ] Department of Physiotherapy, Faculty of Health Sciences, University of Sydney, Sydney, Australia.
          [4 ] School of Public Health, Physiotherapy and Population Science, University College Dublin, Dublin, Ireland.
          Article
          S1063-4584(15)00207-1
          10.1016/j.joca.2015.02.163
          25749012
          a8b7d5fc-7d8a-4fe1-aea2-2daf13258f6e
          Copyright © 2015 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
          History

          Central hyperexcitability,Knee osteoarthritis,Pain processing,Sensitization

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