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      The Fourth Trimester: a Time for Enhancing Transitions in Cardiovascular Care

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          Abstract

          Purpose of Review

          The “fourth trimester” concept, defined as the first 12 weeks after delivery (and beyond), is a critical window of time for clinicians to intervene to optimize women’s cardiovascular health after pregnancy. A timely and comprehensive postpartum cardiovascular assessment should be performed in all women following delivery in order to (1) follow up medical conditions present prior to conception, (2) evaluate symptoms and signs of common postpartum complications, and (3) identify risk factors and prevent future adverse cardiovascular outcomes. In this review, we aim to discuss major maternal cardiovascular risk factors such as hypertensive disorders of pregnancy, gestational diabetes mellitus, postpartum weight retention, and postpartum depression, as well as lactation as a potential protective risk modifying factor. Additionally, we will review effectiveness of outpatient interventions to enhance transitions in cardiovascular care during the fourth trimester.

          Recent Findings

          A seamless hand-off from obstetric to primary care, and potentially cardiology, is needed for early detection and management of hypertension, weight, glycemic control, stress and mood, and long-term cardiovascular risk. Additionally, the use of telemedicine, blood pressure self-monitoring, remote activity monitoring, and behavioral health coaches are potentially feasible modalities to augment clinic-based care for cardiovascular risk factors and weight management, but additional studies are needed to study their long-term effectiveness.

          Summary

          Development of a comprehensive postpartum care plan with careful consideration of each patient’s risk profile and access to resources is critical to improve maternal morbidity and mortality, reduce health disparities, and achieve long-term cardiovascular health for women. Supporting postpartum well-being of women during this transition period requires a multidisciplinary approach, especially primary care engagement, and planning should start before delivery.

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          Most cited references95

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          Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect.

          The importance of breastfeeding in low-income and middle-income countries is well recognised, but less consensus exists about its importance in high-income countries. In low-income and middle-income countries, only 37% of children younger than 6 months of age are exclusively breastfed. With few exceptions, breastfeeding duration is shorter in high-income countries than in those that are resource-poor. Our meta-analyses indicate protection against child infections and malocclusion, increases in intelligence, and probable reductions in overweight and diabetes. We did not find associations with allergic disorders such as asthma or with blood pressure or cholesterol, and we noted an increase in tooth decay with longer periods of breastfeeding. For nursing women, breastfeeding gave protection against breast cancer and it improved birth spacing, and it might also protect against ovarian cancer and type 2 diabetes. The scaling up of breastfeeding to a near universal level could prevent 823,000 annual deaths in children younger than 5 years and 20,000 annual deaths from breast cancer. Recent epidemiological and biological findings from during the past decade expand on the known benefits of breastfeeding for women and children, whether they are rich or poor.
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              , (2013)
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                Author and article information

                Contributors
                edonnell@jhmi.edu
                Journal
                Curr Cardiovasc Risk Rep
                Curr Cardiovasc Risk Rep
                Current Cardiovascular Risk Reports
                Springer US (New York )
                1932-9520
                1932-9563
                21 September 2022
                : 1-11
                Affiliations
                [1 ]GRID grid.21107.35, ISNI 0000 0001 2171 9311, Division of Cardiology, , Johns Hopkins University School of Medicine, ; Baltimore, MD 21287 USA
                [2 ]GRID grid.21107.35, ISNI 0000 0001 2171 9311, Department of Medicine, , Johns Hopkins University School of Medicine, ; MD 21287 Baltimore, USA
                [3 ]GRID grid.413480.a, ISNI 0000 0004 0440 749X, Heart and Vascular Center, , Dartmouth-Hitchcock Medical Center, ; NH Lebanon, USA
                [4 ]GRID grid.21107.35, ISNI 0000 0001 2171 9311, Division of Maternal Fetal Medicine, Department of Gynecology and Obstetrics, , Johns Hopkins University School of Medicine, ; Baltimore, MD 21287 USA
                [5 ]GRID grid.21107.35, ISNI 0000 0001 2171 9311, Division of General Internal Medicine, , Johns Hopkins School of Medicine, ; Baltimore, MD 21287 USA
                [6 ]GRID grid.25879.31, ISNI 0000 0004 1936 8972, Division of Cardiology, , University of Pennsylvania Perelman School of Medicine, ; Philadelphia, PA USA
                [7 ]GRID grid.411935.b, ISNI 0000 0001 2192 2723, Division of Cardiology, , Johns Hopkins Hospital, ; 600 N. Wolfe Street, Blalock 524-B, Baltimore, MD 21287 USA
                Article
                706
                10.1007/s12170-022-00706-x
                9490714
                36159207
                a72559bb-2f5e-44fa-a258-cd0d99831dd1
                © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

                This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

                History
                : 25 August 2022
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/100000062, National Institute of Diabetes and Digestive and Kidney Diseases;
                Award ID: R01DK127222
                Award ID: R18DK122416
                Award Recipient :
                Funded by: FundRef http://dx.doi.org/10.13039/100000050, National Heart, Lung, and Blood Institute;
                Award ID: K23 HL153667
                Award Recipient :
                Funded by: FundRef http://dx.doi.org/10.13039/100007880, Johns Hopkins University;
                Award ID: Amato Fund in Women's Health Research
                Award Recipient :
                Categories
                Women and Heart Disease (M. Gold, Section Editor)

                Cardiovascular Medicine
                fourth trimester,adverse pregnancy outcomes,cardiovascular disease,prevention,blood pressure control,weight management

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