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      Barriers and Facilitators to Clinician Readiness to Provide Emergency Department–Initiated Buprenorphine

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          Abstract

          This qualitative analysis surveys barriers and facilitators of readiness to initiate buprenorphine administration in the emergency department and identifies opportunities to promote readiness among clinicians to treat patients with opioid use disorder.

          Key Points

          Question

          What are the key barriers and facilitators for clinician initiation of buprenorphine in the ED with referral for the treatment of opioid use disorder?

          Findings

          A mixed-methods evaluation of 268 attending physicians, resident physicians, and advanced practice clinicians in academic emergency departments found that 9 of 258 (3.5%) reported completion of Drug Addiction Treatment Act of 2000 training, and 56 of 268 (20.9%) had high levels of readiness to prescribe buprenorphine in the emergency department. Key barriers included lack of training and experience in treating opioid use disorder, concerns about ability to link to ongoing care, and competing needs for time and resources in a busy emergency department.

          Meaning

          Although few emergency department clinicians in this study had high levels of readiness to initiate buprenorphine with referral for ongoing treatment, many expressed a willingness to learn with sufficient support, indicating the importance of clinician and system-level changes.

          Abstract

          Importance

          Treatment of opioid use disorder (OUD) with buprenorphine decreases opioid use and prevents morbidity and mortality. Emergency departments (EDs) are an important setting for buprenorphine initiation for patients with untreated OUD; however, readiness varies among ED clinicians.

          Objective

          To characterize barriers and facilitators of readiness to initiate buprenorphine for the treatment of OUD in the ED and identify opportunities to promote readiness across multiple clinician types.

          Design, Setting, and Participants

          Using data collected from April 1, 2018, to January 11, 2019, this mixed-methods formative evaluation grounded in the Promoting Action on Research Implementation in Health Services framework included 4 geographically diverse academic EDs. Attending physicians (n = 113), residents (n = 107), and advanced practice clinicians (APCs) (n = 48) completed surveys electronically distributed to all ED clinicians (n = 396). A subset of participants (n = 74) also participated in 1 of 11 focus group discussions. Data were analyzed from June 1, 2018, to February 22, 2020.

          Main Outcomes and Measures

          Clinician readiness to initiate buprenorphine and provide referral for ongoing treatment for patients with OUD treated in the ED was assessed using a visual analog scale. Responders (268 of 396 [67.7%]) were dichotomized as less ready (scores 0-6) or most ready (scores 7-10). An ED-adapted Organizational Readiness to Change Assessment (ORCA) and 11 focus groups were used to assess ratings and perspectives on evidence and context-related factors to promote ED-initiated buprenorphine with referral for ongoing treatment, respectively.

          Results

          Among the 268 survey respondents (153 of 260 were men [58.8%], with a mean [SD] of 7.1 [9.8] years since completing formal training), 56 (20.9%) indicated readiness to initiate buprenorphine for ED patients with OUD. Nine of 258 (3.5%) reported Drug Addiction Treatment Act of 2000 training completion. Compared with those who were less ready, clinicians who were most ready to initiate buprenorphine had higher mean scores across all ORCA Evidence subscales (3.50 [95% CI, 3.35-3.65] to 4.33 [95% CI, 4.13-4.53] vs 3.11 [95% CI, 3.03-3.20] to 3.60 [95% CI, 3.49-3.70]; P < .001) and on the Slack Resources of the ORCA Context subscales (3.32 [95% CI, 3.08-3.55] vs 3.0 [95% CI, 2.87-3.12]; P = .02). Barriers to ED-initiated buprenorphine included lack of training and experience in treating OUD with buprenorphine, concerns about ability to link to ongoing care, and competing needs and priorities for ED time and resources. Facilitators to ED-initiated buprenorphine included receiving education and training, development of local departmental protocols, and receiving feedback on patient experiences and gaps in quality of care.

          Conclusions and Relevance

          Only a few ED clinicians had a high level of readiness to initiate buprenorphine; however, many expressed a willingness to learn with sufficient supports. Efforts to promote adoption of ED-initiated buprenorphine will require clinician and system-level changes.

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          Point-of-care ultrasonography.

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            Evaluating the successful implementation of evidence into practice using the PARiHS framework: theoretical and practical challenges

            Background The PARiHS framework (Promoting Action on Research Implementation in Health Services) has proved to be a useful practical and conceptual heuristic for many researchers and practitioners in framing their research or knowledge translation endeavours. However, as a conceptual framework it still remains untested and therefore its contribution to the overall development and testing of theory in the field of implementation science is largely unquantified. Discussion This being the case, the paper provides an integrated summary of our conceptual and theoretical thinking so far and introduces a typology (derived from social policy analysis) used to distinguish between the terms conceptual framework, theory and model – important definitional and conceptual issues in trying to refine theoretical and methodological approaches to knowledge translation. Secondly, the paper describes the next phase of our work, in particular concentrating on the conceptual thinking and mapping that has led to the generation of the hypothesis that the PARiHS framework is best utilised as a two-stage process: as a preliminary (diagnostic and evaluative) measure of the elements and sub-elements of evidence (E) and context (C), and then using the aggregated data from these measures to determine the most appropriate facilitation method. The exact nature of the intervention is thus determined by the specific actors in the specific context at a specific time and place. In the process of refining this next phase of our work, we have had to consider the wider issues around the use of theories to inform and shape our research activity; the ongoing challenges of developing robust and sensitive measures; facilitation as an intervention for getting research into practice; and finally to note how the current debates around evidence into practice are adopting wider notions that fit innovations more generally. Summary The paper concludes by suggesting that the future direction of the work on the PARiHS framework is to develop a two-stage diagnostic and evaluative approach, where the intervention is shaped and moulded by the information gathered about the specific situation and from participating stakeholders. In order to expedite the generation of new evidence and testing of emerging theories, we suggest the formation of an international research implementation science collaborative that can systematically collect and analyse experiences of using and testing the PARiHS framework and similar conceptual and theoretical approaches. We also recommend further refinement of the definitions around conceptual framework, theory, and model, suggesting a wider discussion that embraces multiple epistemological and ontological perspectives.
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              PARIHS revisited: from heuristic to integrated framework for the successful implementation of knowledge into practice

              Background The Promoting Action on Research Implementation in Health Services, or PARIHS framework, was first published in 1998. Since this time, work has been ongoing to further develop, refine and test it. Widely used as an organising or conceptual framework to help both explain and predict why the implementation of evidence into practice is or is not successful, PARIHS was one of the first frameworks to make explicit the multi-dimensional and complex nature of implementation as well as highlighting the central importance of context. Several critiques of the framework have also pointed out its limitations and suggested areas for improvement. Discussion Building on the published critiques and a number of empirical studies, this paper introduces a revised version of the framework, called the integrated or i-PARIHS framework. The theoretical antecedents of the framework are described as well as outlining the revised and new elements, notably, the revision of how evidence is described; how the individual and teams are incorporated; and how context is further delineated. We describe how the framework can be operationalised and draw on case study data to demonstrate the preliminary testing of the face and content validity of the revised framework. Summary This paper is presented for deliberation and discussion within the implementation science community. Responding to a series of critiques and helpful feedback on the utility of the original PARIHS framework, we seek feedback on the proposed improvements to the framework. We believe that the i-PARIHS framework creates a more integrated approach to understand the theoretical complexity from which implementation science draws its propositions and working hypotheses; that the new framework is more coherent and comprehensive and at the same time maintains it intuitive appeal; and that the models of facilitation described enable its more effective operationalisation. Electronic supplementary material The online version of this article (doi:10.1186/s13012-016-0398-2) contains supplementary material, which is available to authorized users.
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                Author and article information

                Journal
                JAMA Netw Open
                JAMA Netw Open
                JAMA Netw Open
                JAMA Network Open
                American Medical Association
                2574-3805
                11 May 2020
                May 2020
                11 May 2020
                : 3
                : 5
                : e204561
                Affiliations
                [1 ]Department of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut
                [2 ]Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut
                [3 ]Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut
                [4 ]Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, New York
                [5 ]Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio
                [6 ]Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
                [7 ]Department of Emergency Medicine, University of Washington, Seattle
                [8 ]Department of Health Policy and Management, Yale School of Public Health, New Haven, Connecticut
                Author notes
                Article Information
                Accepted for Publication: February 28, 2020.
                Published: May 11, 2020. doi:10.1001/jamanetworkopen.2020.4561
                Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2020 Hawk KF et al. JAMA Network Open.
                Corresponding Author: Kathryn F. Hawk, MD, Department of Emergency Medicine, Yale School of Medicine, 464 Congress Ave, Ste 260, New Haven, CT 06519 ( kathryn.hawk@ 123456yale.edu ).
                Author Contributions: Drs Hawk and Chawarski had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
                Concept and design: Hawk, D’Onofrio, Chawarski, O’Connor, Martel, Pantalon, Fiellin, Edelman.
                Acquisition, analysis, or interpretation of data: Hawk, D’Onofrio, Chawarski, O’Connor, Cowan, Lyons, Richardson, Rothman, Whiteside, Owens, Coupet, Pantalon, Curry, Fiellin, Edelman.
                Drafting of the manuscript: Hawk, Chawarski, O’Connor, Martel, Pantalon, Edelman.
                Critical revision of the manuscript for important intellectual content: Hawk, D’Onofrio, Chawarski, O’Connor, Cowan, Lyons, Richardson, Rothman, Whiteside, Owens, Coupet, Pantalon, Curry, Fiellin, Edelman.
                Statistical analysis: Hawk, Chawarski, Curry.
                Obtained funding: D’Onofrio, Chawarski, Owens, Pantalon, Fiellin.
                Administrative, technical, or material support: Cowan, Lyons, Richardson, Rothman, Whiteside, Owens, Martel, Coupet, Pantalon, Fiellin.
                Supervision: D’Onofrio, Lyons, Rothman, Owens, Pantalon, Fiellin.
                Conflict of Interest Disclosures: Dr Hawk reported receiving grants from the National Institute on Drug Abuse (NIDA)/National Institutes of Health (NIH) during the conduct of this study. Dr D’Onofrio reported receiving grants from the NIDA/NIH, during the conduct of the study. Dr Chawarski reported receiving grants from the NIDA/NIH during the conduct of the study. Dr Cowan reported receiving grants from the NIDA/NIH during the conduct of the study. Dr Lyons reported receiving grants from the NIDA/NIH during the conduct of the study. Dr Richardson reported receiving grants from the NIDA/NIH during the conduct of the study. Dr Rothman reported receiving grants from the NIDA/NIH during the conduct of the study. Dr Whiteside reported receiving grants from the NIDA Center for the Clinical Trials Network (CTN) and the NIDA/NIH during the conduct of the study. Ms Owens reported receiving grants from the NIDA/NIH during the conduct of the study. Ms Martel reported receiving grants from the NIDA/NIH during the conduct of the study. Dr Pantalon reported receiving personal fees from Center for Progressive Recovery outside the submitted work and funding from the NIDA/NIH during the conduct of the study. Dr Fiellin reported receiving grants from the NIDA/NIH during the conduct of the study and honoraria from Springer Nature, Boston Medical Center, University of New South Wales, University of Alabama, Birmingham, US Department of Justice, Tufts University, American Society of Addiction Medicine, American Academy of Addiction Psychiatry, Boston University, and University of Kentucky. Dr Edelman reported receiving grants from the NIDA/NIH during the conduct of the study. No other disclosures were reported.
                Funding/Support: This study was supported by grant 5UG1DA015831-15 (CTN-0069) from the NIDA/NIH and grant K12 2K12 DA033312-06 from the NIDA/NIH (Dr Coupet).
                Role of the Funder/Sponsor: The NIDA collaborated in the design and conduct of the study and reviewed and provided comments for consideration in drafts of the manuscript. They were not involved in the data collection, management, or analysis and did not have final approval of the manuscript for submission.
                Additional Contributions: Christian Helfrich, MPH, PhD, Health Services University of Washington School of Public Health, provided guidance and assistance in the modification and scoring of the Organizational Readiness to Change Assessment for use in the emergency department on the topic of initiating buprenorphine treatment. He was not compensated for this work.
                Article
                zoi200218
                10.1001/jamanetworkopen.2020.4561
                7215257
                32391893
                9ff841f0-0ec2-4e5d-a3a8-cbc906629704
                Copyright 2020 Hawk KF et al. JAMA Network Open.

                This is an open access article distributed under the terms of the CC-BY License.

                History
                : 18 December 2019
                : 28 February 2020
                Categories
                Research
                Original Investigation
                Online Only
                Substance Use and Addiction

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