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      Risk of infection in patients with atopic dermatitis treated with dupilumab: A meta-analysis of randomized controlled trials.

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          Abstract

          Atopic dermatitis (AD) is characterized by skin barrier defects, T helper type 2 cell activation, and increased risk for cutaneous and extracutaneous infections. In clinical trials, dupilumab appeared to decrease rates of skin infections in AD.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): J. Am. Acad. Dermatol.
          Title: Journal of the American Academy of Dermatology
          Publisher: Elsevier BV
          ISSN (Electronic): 1097-6787
          ISSN (Print): 0190-9622
          Publication date (Electronic): Jan 2018
          Volume: 78
          Issue: 1
          Affiliations
          [1 ] Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
          [2 ] Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Division of Dermatology, Department of Medicine and Women's College Research Institute, Women's College Hospital, Toronto, Ontario, Canada; Department of Dermatology, Brown University, Providence, Rhode Island. Electronic address: aaron.drucker@wchospital.ca.
          Article
          Publisher Item ID: S0190-9622(17)32457-X
          DOI: 10.1016/j.jaad.2017.09.052
          PubMed ID: 28987493
          SO-VID: 9e255704-ba88-40f9-8c34-8fec7426b787
          History

          Keywords: dupilumab,herpes infections,infections,meta-analysis,atopic dermatitis,atopic eczema
          Data availability:
          Keywords: dupilumab, herpes infections, infections, meta-analysis, atopic dermatitis, atopic eczema

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