The FGFR Landscape in Cancer: Analysis of 4,853 Tumors by Next-Generation Sequencing.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Molecular profiling may have prognostic and predictive value, and is increasingly used in the clinical setting. There are more than a dozen fibroblast growth factor receptor (FGFR) inhibitors in development. Optimal therapeutic application of FGFR inhibitors requires knowledge of the rates and types of FGFR aberrations in a variety of cancer types.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Clin. Cancer Res.

Title: Clinical cancer research : an official journal of the American Association for Cancer Research

Publisher: American Association for Cancer Research (AACR)

ISSN: 1078-0432

ISSN (Print): 1078-0432

Publication date (Electronic): Jan 01 2016

Volume: 22

Issue: 1

Affiliations

[1 ] Center for Personalized Cancer Therapy, UC San Diego Moores Cancer Center, La Jolla, California. thelsten@ucsd.edu.

[2 ] N-of-One, Inc., Lexington, Massachusetts.

[3 ] Center for Personalized Cancer Therapy, UC San Diego Moores Cancer Center, La Jolla, California.

Article

Publisher Item ID: 1078-0432.CCR-14-3212

DOI: 10.1158/1078-0432.CCR-14-3212

PubMed ID: 26373574

SO-VID: 9953ede3-99d3-45a0-abe4-51d4ad92e8a4

History

Data availability:

Comments

Comment on this article

scite_

0

Smart Citations

0

Citing PublicationsSupportingMentioningContrasting

View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.

Cited by 348

See all cited by