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      Assessing the impact of screening, early identification and intervention programmes for chronic kidney disease: protocol for a scoping review

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          Abstract

          Introduction

          Chronic kidney disease (CKD) is a major threat to public health, especially in low-income and lower middle-income countries, where resources for treating patients with advanced CKD are scarce. Although early CKD identification and intervention hold promise for reducing the burden of CKD and risk factors, it remains unclear if an uniform strategy can be applicable across all income groups. The aim of this scoping review is to synthesise available evidence on early CKD identification programmes in all world regions and income groups. The study will also identify efforts that have been made to use interventions and implementation of early identification programmes for CKD across countries and income groups.

          Methods and analysis

          This review will be guided by the methodological framework for conducting scoping studies developed by Arksey and O’Malley. Empirical (Medline, Embase, Cochrane Library, CINAHL, ISI Web of Science and PsycINFO) and grey literature references will be searched to identify studies on CKD screening, early identification and interventions across all populations. Two reviewers will independently screen references in consecutive stages of title/abstract screening and then full-text screening. We will use a general descriptive overview, tabular summaries and content analysis on extracted data.

          Ethics and dissemination

          The findings from our planned scoping review will enable us to identify items in early identification programmes that can be used in developing screening toolkits for CKD. We will disseminate our findings using traditional approaches that include open-access peer-reviewed publication, scientific presentations and a white paper (call to action) report. Ethical approval will not be required for this scoping review as the data will be extracted from already published studies.

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          Most cited references50

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          PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation

          Scoping reviews, a type of knowledge synthesis, follow a systematic approach to map evidence on a topic and identify main concepts, theories, sources, and knowledge gaps. Although more scoping reviews are being done, their methodological and reporting quality need improvement. This document presents the PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) checklist and explanation. The checklist was developed by a 24-member expert panel and 2 research leads following published guidance from the EQUATOR (Enhancing the QUAlity and Transparency Of health Research) Network. The final checklist contains 20 essential reporting items and 2 optional items. The authors provide a rationale and an example of good reporting for each item. The intent of the PRISMA-ScR is to help readers (including researchers, publishers, commissioners, policymakers, health care providers, guideline developers, and patients or consumers) develop a greater understanding of relevant terminology, core concepts, and key items to report for scoping reviews.
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            Scoping studies: towards a methodological framework

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              Scoping studies: advancing the methodology

              Background Scoping studies are an increasingly popular approach to reviewing health research evidence. In 2005, Arksey and O'Malley published the first methodological framework for conducting scoping studies. While this framework provides an excellent foundation for scoping study methodology, further clarifying and enhancing this framework will help support the consistency with which authors undertake and report scoping studies and may encourage researchers and clinicians to engage in this process. Discussion We build upon our experiences conducting three scoping studies using the Arksey and O'Malley methodology to propose recommendations that clarify and enhance each stage of the framework. Recommendations include: clarifying and linking the purpose and research question (stage one); balancing feasibility with breadth and comprehensiveness of the scoping process (stage two); using an iterative team approach to selecting studies (stage three) and extracting data (stage four); incorporating a numerical summary and qualitative thematic analysis, reporting results, and considering the implications of study findings to policy, practice, or research (stage five); and incorporating consultation with stakeholders as a required knowledge translation component of scoping study methodology (stage six). Lastly, we propose additional considerations for scoping study methodology in order to support the advancement, application and relevance of scoping studies in health research. Summary Specific recommendations to clarify and enhance this methodology are outlined for each stage of the Arksey and O'Malley framework. Continued debate and development about scoping study methodology will help to maximize the usefulness and rigor of scoping study findings within healthcare research and practice.
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                Author and article information

                Journal
                BMJ Open
                BMJ Open
                bmjopen
                bmjopen
                BMJ Open
                BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                2044-6055
                2021
                16 December 2021
                : 11
                : 12
                : e053857
                Affiliations
                [1 ]departmentDivision of Nephrology and Hypertension , University of Cape Town , Cape Town, South Africa
                [2 ]departmentDepartment of Medicine & Dentistry , University of Alberta , Edmonton, Alberta, Canada
                [3 ]departmentRichard Bright Renal Unit , North Bristol NHS Trust , Westbury on Trym, UK
                [4 ]UK Renal Registry , Bristol, UK
                [5 ]departmentDepartment of Medicine , Nazarbaev Universitet , Nur-Sultan, Kazakhstan
                [6 ]departmentDepartment of Medicine , Komfo Anokye Teaching Hospital , Kumasi, Ghana
                [7 ]departmentJohn W. Scott Health Sciences Library , University of Alberta , Edmonton, Alberta, Canada
                [8 ]departmentDepartment of Internal Medicine and Subspecialties , University of Yaounde I , Yaounde, Cameroon
                [9 ]departmentGlobal Operations Centre , International Society of Nephrology , Brussels, Belgium
                [10 ]departmentNursing School , Pontifícia Universidade Católica do Rio Grande do Sul , Porto Alegre, Brazil
                [11 ]departmentDepartment of Medicine , The University of Tokyo Graduate School of Medicine , Bunkyo-ku, Japan
                [12 ]departmentDepartment of Nephrology , Instituto Nacional de Cardiología Ignacio Chávez , Mexico City, Mexico
                [13 ]departmentDOPPS Program , Arbor Research Collaborative for Health , Ann Arbor, Michigan, USA
                [14 ]departmentDepartment of Medicine , Charles University , Praha, Czech Republic
                [15 ]departmentDepartment of Medicine , The University of British Columbia Faculty of Medicine , Vancouver, British Columbia, Canada
                [16 ]The George Institute for Global Health India , New Delhi, Delhi, India
                Author notes
                [Correspondence to ] Dr Ikechi G Okpechi; ikechi.okpechi@ 123456uct.ac.za
                Author information
                http://orcid.org/0000-0002-6545-9715
                Article
                bmjopen-2021-053857
                10.1136/bmjopen-2021-053857
                8679109
                34916325
                971aa11b-d80f-4c32-8d46-7ad3bd841172
                © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

                This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See:  http://creativecommons.org/licenses/by-nc/4.0/.

                History
                : 26 May 2021
                : 11 November 2021
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/100004325, AstraZeneca;
                Award ID: No grant number
                Categories
                Renal Medicine
                1506
                1728
                Protocol
                Custom metadata
                unlocked

                Medicine
                chronic renal failure,end stage renal failure,adult nephrology,epidemiology
                Medicine
                chronic renal failure, end stage renal failure, adult nephrology, epidemiology

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