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      Advances in the Management of Aphakia

      editorial
      1 , , 1 , 2 , 3
      Journal of Ophthalmology
      Hindawi

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          Abstract

          Aphakia is a condition in which the crystalline lens of the eye is not present in its normal position following surgical removal, perforating injury, congenital anomaly, or dislocation of the lens. It causes loss of accommodation, high hyperopia, and anisometropia. The management of aphakia can be either conservative (spectacles or contact lenses) or surgical [1]. Surgical management of aphakia concerns both anterior and posterior segment surgeons and can be a real challenge, especially in paediatric patients where the visual system is still immature; because the child's eye continues to grow during childhood, certain complications are not acceptable [2–4]. In this Special Issue published in the Journal of Ophthalmology, Sidiropoulos et al. presented a new sutureless scleral fixation technique using a single-piece foldable acrylic Carlevale intraocular lens which they inserted in 27 eyes of 27 patients with poor capsular support [5]. The mean postoperative refraction at 6 months was −0.5 ± 0.99 D, while the postoperative complications were either resolved spontaneously or treated medically without the need for further surgery. Massa and colleagues from the Geneva University Hospitals presented the SWISS IOL, a new minimally invasive technique for the scleral fixation of intraocular lenses (IOLs) in eyes without capsular support [6]. The postoperative spherical equivalent refraction ranged between −0.75 and −2.25, and no perioperative or postoperative complications were recorded while all IOLs were well centered postoperatively without any dislocation or tilt. Finally, Karasavvidou and colleagues from the Nottingham University Hospitals provided a literature review on the surgical management of paediatric aphakia in the absence of sufficient capsular support presenting the advantages and disadvantages of each surgical technique [7]. Georgios D. Panos Craig Wilde Paris Tranos Zisis Gatzioufas

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          Most cited references7

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          Iris claw lenses in aphakia.

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            Visual Rehabilitation in Pediatric Aphakia.

            The management of childhood cataract begins at the initial contact with the family and typically extends far into the child's future. Decisions affecting long-term care and visual outcomes are often made in these initial preoperative encounters. Treatment will vary depending on whether the cataract is unilateral or bilateral and whether it is infantile onset or later. Thorough discussion of the treatment options is needed, especially with description of the life-long management issues for the child. Visual outcomes will vary, with the best visual acuity results being observed in older children with bilateral cataracts. Visual rehabilitation of children with unilateral cataract requires use of a contact lens or an intraocular lens (IOL) for the best result with a chance for binocularity. Only about 50% of eyes with unilateral infantile cataract will develop vision of better than 20/200. For bilateral cataracts, both contacts and IOLs can be used, as well as aphakic glasses. Excellent visual outcomes are typical unless glaucoma develops, which occurs in up to 30% of cases. Cataract surgery after 1 year of age is associated with substantially better visual outcomes. The use of an IOL is most commonly accepted and performed for cataract in one or both eyes after 1 year of age. Prior to 1 year of age, significantly more secondary surgical procedures are required to manage opacification of the optical axis with the use of an IOL compared with the use of surgery and contact lens correction. Amblyopia therapy for unilateral cataract needs be continuous from the time of surgery until at least 8 years of age. It is often difficult to perform this therapy over such a long time period, with compliance with less than 30% of prescribed time during infancy at 5 years after surgery.
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              Intraocular Lens Techniques in Pediatric Eyes with Insufficient Capsular Support: Complications and Outcomes.

              Intraocular lens (IOL) implantation in pediatric eyes with insufficient capsular support is challenging and there are multiple IOL options. These include placement of an IOL within the capsular bag with a capsular tension ring, a scleral-fixated posterior-chamber IOL (PCIOL) with or without capsular tension segment or ring, an intra-scleral fixated IOL, an iris-sutured PCIOL, or an anterior chamber iris-fixated IOL. We reviewed 48 articles and 1 published abstract describing the surgical techniques, complications and visual outcomes of different IOL options in the management of aphakic pediatric eyes with insufficient capsular support. The present review found that the visual acuity outcomes of various IOLs are comparable. Furthermore, each IOL design and surgical technique has different rates of serious complications, including IOL dislocation or decentration, intraocular hemorrhage, glaucoma, endothelial cell loss, and endophthalmitis. An understanding of the risks and benefits of different IOL designs is important for counseling patients and families.
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                Author and article information

                Contributors
                Journal
                J Ophthalmol
                J Ophthalmol
                JOPH
                Journal of Ophthalmology
                Hindawi
                2090-004X
                2090-0058
                2022
                27 March 2022
                : 2022
                : 9841758
                Affiliations
                1Department of Ophthalmology, Queen's Medical Centre, Nottingham University Hospitals, Nottingham, UK
                2Ophthalmica Eye Institute, Thessaloniki, Greece
                3Department of Ophthalmology, Basel University Hospitals, Basel, Switzerland
                Author information
                https://orcid.org/0000-0001-8399-7456
                https://orcid.org/0000-0001-9099-5336
                Article
                10.1155/2022/9841758
                8977344
                35388354
                96e9f643-e3d0-4b12-9b49-9679a717ef21
                Copyright © 2022 Georgios D. Panos et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 8 March 2022
                : 8 March 2022
                Categories
                Editorial

                Ophthalmology & Optometry
                Ophthalmology & Optometry

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