Proposed clinical management of pregnancies after combined screening for pre-eclampsia at 35-37 weeks' gestation.

Panaitescu, A M; Wright, D.; Militello, A; Akolekar, R; Nicolaides, K H

doi:10.1002/uog.17419

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Proposed clinical management of pregnancies after combined screening for pre-eclampsia at 35-37 weeks' gestation.

Author(s): A M Panaitescu, D Wright, A Militello, R Akolekar, K H Nicolaides

Publication date: 2017-09-01

Journal: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology

Publisher: Wiley

Keywords: placental growth factor, mean arterial pressure, pyramid of antenatal care, uterine artery pulsatility index, soluble fms-like tyrosine kinase-1, pre-eclampsia

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Abstract

To estimate the patient-specific risk of pre-eclampsia (PE) at 35-37 weeks' gestation by a combination of maternal characteristics and medical history with multiples of the median (MoM) values of mean arterial pressure (MAP), uterine artery pulsatility index (UtA-PI), serum placental growth factor (PlGF) and serum soluble fms-like tyrosine kinase-1 (sFlt-1), and stratify women into high-, intermediate- and low-risk management groups.