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      Effect of Laparoscopic‐assisted Gastropexy on Gastrointestinal Transit Time in Dogs

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          Abstract

          Background

          Prophylactic gastropexy has been promoted as a means of preventing gastric volvulus during gastric dilatation and volvulus ( GDV) syndrome. Little is known about the impact of gastropexy on gastrointestinal transit time.

          Hypothesis

          Laparoscopic‐assisted gastropexy ( LAG) will not alter gastrointestinal transit times when comparing gastric ( GET), small and large bowel ( SLBTT), and whole gut transit times ( TTT) before and after surgery.

          Animals

          10 healthy client‐owned large‐breed dogs.

          Methods

          Prospective clinical trial. Before surgery, all dogs underwent physical examination and diagnostic evaluation to ensure normal health status. Dogs were fed a prescription diet for 6 weeks before determination of gastrointestinal transit with a wireless motility capsule. LAG was then performed, and dogs were fed the diet for 6 additional weeks. Measurement of transit times was repeated 6 weeks after surgery.

          Results

          Ten dogs of various breeds at‐risk for GDV were enrolled. No complications were encountered associated with surgery or capsule administration. There were no significant differences in GET 429 [306–1,370] versus 541 [326–1,298] ( P = 0.80), SLBTT 1,243 [841–3,070] versus 1,540 [756–2,623] ( P = 0.72), or TTT 1,971 [1,205–3,469] versus 1,792 [1,234–3,343] minutes (median, range) ( P = 0.65) before and after LAG.

          Conclusions and Clinical Importance

          An effect of LAG on gastrointestinal transit time was not identified, and wireless motility capsule can be safely administered in dogs after LAG.

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          Most cited references19

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          Evaluation of gastrointestinal transit in clinical practice: position paper of the American and European Neurogastroenterology and Motility Societies.

          Disorders of gastrointestinal (GI) transit and motility are common, and cause either delayed or accelerated transit through the stomach, small intestine or colon, and affect one or more regions. Assessment of regional and/or whole gut transit times can provide direct measurements and diagnostic information to explain the cause of symptoms, and plan therapy. Recently, several newer diagnostic tools have become available. The American and European Neurogastroenterology and Motility Societies undertook this review to provide guidelines on the indications and optimal methods for the use of transit measurements in clinical practice. This was based on evidence of validation including performance characteristics, clinical significance, and strengths of various techniques. The tests include measurements of: gastric emptying with scintigraphy, wireless motility capsule, and (13)C breath tests; small bowel transit with breath tests, scintigraphy, and wireless motility capsule; and colonic transit with radioopaque markers, wireless motility capsule, and scintigraphy. Based on the evidence, consensus recommendations are provided for each technique and for the evaluations of regional and whole gut transit. In summary, tests of gastrointestinal transit are available and useful in the evaluation of patients with symptoms suggestive of gastrointestinal dysmotility, since they can provide objective diagnosis and a rational approach to patient management. © 2010 Blackwell Publishing Ltd.
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            Wireless capsule motility: comparison of the SmartPill GI monitoring system with scintigraphy for measuring whole gut transit.

            Assessment of whole gut transit, by radio-opaque markers or scintigraphy, is used to evaluate patients with constipation for slow gastrointestinal transit. Wireless capsule motility, using the SmartPill GI monitoring system, samples and transmits intraluminal pH, pressure, and temperature data from a capsule at regular intervals as it traverses through the gastrointestinal tract; from these, gastric emptying and whole gastrointestinal tract transit can be assessed. The objective of this study was to compare the SmartPill with whole gut transit scintigraphy to determine whether the SmartPill system could serve as a test for measurement of whole gut motility and transit. Ten healthy, asymptomatic subjects underwent simultaneous whole gut scintigraphy and SmartPill assessment of whole gut transit. All subjects completed the study per protocol and experienced natural passage of the pill. Capsule residence time in the stomach correlated very strongly with percent gastric retention of the Tc-99 radiolabel at 120 min (r = 0.95) and at 240 min (r = 0.73). Small bowel contraction-min(-1) measured by the SmartPill correlated with small bowel transit % (r = 0.69; P = 0.05) and with isotopic colonic geometric center at 24 h after ingestion (r = 0.70, P = 0.024). Capsule transit time correlated with scintigraphic assessment of whole gut transit. SmartPill capsule assessment of gastric emptying and whole gut transit compares favorably with that of scintigraphy. Wireless capsule motility shows promise as a useful diagnostic test to evaluate patients for GI transit disorders and to study the effect of prokinetic agents on GI transit.
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              Prospective evaluation of two intracorporeally sutured prophylactic laparoscopic gastropexy techniques compared with laparoscopic-assisted gastropexy in dogs.

              To report technique, surgical time, complication rate, and postoperative activity in dogs undergoing 2 intracorporeally-sutured total laparoscopic gastropexy (TLG) techniques compared with a laparoscopic-assisted gastropexy (LAG) technique.
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                Author and article information

                Contributors
                wculp@ucdavis.edu
                Journal
                J Vet Intern Med
                J. Vet. Intern. Med
                10.1111/(ISSN)1939-1676
                JVIM
                Journal of Veterinary Internal Medicine
                John Wiley and Sons Inc. (Hoboken )
                0891-6640
                1939-1676
                20 September 2017
                Nov-Dec 2017
                : 31
                : 6 ( doiID: 10.1111/jvim.2017.31.issue-6 )
                : 1680-1685
                Affiliations
                [ 1 ] Departments of Veterinary Surgical and Radiological Sciences (Balsa, Culp, Johnson, Mayhew), and Medicine and Epidemiology (Marks) School of Veterinary Medicine University of California‐Davis Davis CA
                [ 2 ] Department of Clinical Sciences School of Veterinary Medicine University of Pennsylvania Philadelphia PA
                Author notes
                [*] [* ]Corresponding author: W. Culp, School of Veterinary Medicine, University of California‐Davis, One Garrod Drive, Davis, CA 95616; e‐mail: wculp@ 123456ucdavis.edu
                Author information
                http://orcid.org/0000-0001-6132-156X
                http://orcid.org/0000-0001-7991-702X
                Article
                JVIM14816
                10.1111/jvim.14816
                5697196
                28940749
                94eeb860-efc2-486e-abf2-71667c053fa1
                Copyright © 2017 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

                This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

                History
                : 01 May 2017
                : 25 May 2017
                : 24 July 2017
                Page count
                Figures: 3, Tables: 0, Pages: 6, Words: 3969
                Categories
                Standard Article
                SMALL ANIMAL
                Standard Articles
                Gastroenterology
                Custom metadata
                2.0
                jvim14816
                November/December 2017
                Converter:WILEY_ML3GV2_TO_NLMPMC version:5.2.6 mode:remove_FC converted:21.11.2017

                Veterinary medicine
                emptying,endoscopy,minimally invasive,prophylactic
                Veterinary medicine
                emptying, endoscopy, minimally invasive, prophylactic

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