Effective suppression of atrial fibrillation by the antihistaminic agent antazoline: First experimental insights into a novel antiarrhythmic agent.

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Abstract

The antihistaminic antazoline (ANT) was reported to be highly effective and safe for rapid conversion of atrial fibrillation (AF). We therefore analyzed underlying mechanisms in an experimental whole-heart model.

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Journal

Journal ID (iso-abbrev): Cardiovasc Ther

Title: Cardiovascular therapeutics

Publisher: Wiley

ISSN (Electronic): 1755-5922

ISSN (Print): 1755-5914

Publication date (Electronic): Apr 2017

Volume: 35

Issue: 2

Affiliations

[1 ] Division of Clinical and Experimental Electrophysiology, Department of Cardiology and Angiology, University Hospital of Münster, Münster, Germany.

[2 ] Clinic of Exotic Pets, Reptiles, Exotic and Feral Birds, University of Hanover, Hanover, Germany.

[3 ] Märkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, University of Witten-Herdecke, Witten, Germany.

Article

DOI: 10.1111/1755-5922.12244

PubMed ID: 28039911

SO-VID: 9371a25f-3701-45c7-a6dc-fe57396f8b22

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Keywords: Antazoline,Antiarrhythmic drugs,Atrial fibrillation,Flecainide,postrepolarization refractoriness

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Keywords: Antazoline, Antiarrhythmic drugs, Atrial fibrillation, Flecainide, postrepolarization refractoriness

Effective suppression of atrial fibrillation by the antihistaminic agent antazoline: First experimental insights into a novel antiarrhythmic agent.

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Karger: Cardiovascular System

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