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Low serum IGF-1 and occurrence of osteoporotic fractures in postmenopausal women.

Author(s): P. Delmas, E Sornay-Rendu, P Garnero

Publication date: 2000-03-11

Journal: Lancet

Keywords: Aged, Aged, 80 and over, Bone Density, physiology, Female, Fractures, Spontaneous, blood, etiology, Humans, Insulin-Like Growth Factor Binding Protein 3, Insulin-Like Growth Factor I, deficiency, Middle Aged, Osteoporosis, Postmenopausal, Risk Factors

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Abstract

The link between serum insulin-like growth factor 1 (IGF-1) and postmenopausal osteoporosis remains controversial. In this study of healthy postmenopausal women, decreased serum concentrations of IGF-1 were strongly associated with an increased risk of osteoporotic fractures independently of bone-mineral density.

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PubMed ID:: 10752709

DOI:: 10.1016/S0140-6736(99)05463-X

ScienceOpen disciplines: Chemistry

Keywords: Aged,Aged, 80 and over,Bone Density,physiology,Female,Fractures, Spontaneous,blood,etiology,Humans,Insulin-Like Growth Factor Binding Protein 3,Insulin-Like Growth Factor I,deficiency,Middle Aged,Osteoporosis, Postmenopausal,Risk Factors

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ScienceOpen disciplines: Chemistry

Low serum IGF-1 and occurrence of osteoporotic fractures in postmenopausal women.

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