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      Regulation of long non-coding RNAs XIST and ROR induced by homeodomain protein TGIF2LX in colorectal cancer.

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          Abstract

          Homeodomain protein transforming growth factor beta-induced factor 2 like, X-linked (TGIF2 LX) has been demonstrated to act as a transcription factor and regulate cancer cell proliferation. Long non-coding RNAs (lncRNAs) are well known as molecular regulators of colorectal cancer (CRC). Our aim was to evaluate the clinical and biological significance of TGIF2 LX and its effect on lncRNAs regulator of reprogramming (ROR) and X-inactive specific transcript (XIST) expression in CRC cells.

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          Author and article information

          Journal
          J Cancer Res Ther
          Journal of cancer research and therapeutics
          Medknow
          1998-4138
          1998-4138
          Dec 2022
          : 18
          : Supplement
          Affiliations
          [1 ] Department of Biology, School of Basic Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.
          [2 ] Colorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
          [3 ] Department of Genetic, Islamic Azad University, Varamin-Pishva Branch, Varamin, Iran.
          Article
          JCanResTher_2022_18_9_359_317459
          10.4103/jcrt.JCRT_869_20
          36510989
          8c83381a-d9d8-4cae-80a3-d05f7a447eef
          History

          X-linked,HOX gene,Colorectal cancer,transforming growth factor beta-induced factor 2 like,long non-coding RNA,homeodomain protein

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