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      Gallbladder Metastasis from Renal Cell Carcinoma

      case-report

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          Abstract

          A 73-year-old female was operated with radical nephrectomy and cholecystectomy for renal cell carcinoma and suspected gallstones after 9 courses of sunitinib treatment. Gallbladder specimen showed gallbladder metastasis originating from the renal cell carcinoma. Gallbladder metastasis from renal cell carcinoma is rare. Here, we discuss a case of gallbladder metastasis from renal cell carcinoma.

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          The spread of tumors in the human body

          RA Willis, R. WILLIS, R. WILLIS … (1952)
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            Renal cell carcinoma metastatic to the gallbladder or prostate: two case reports.

            Gwendalyn D. King, Maria Centeno, M F Sarosdy … (1995)
            Although metastatic renal cell carcinoma (RCC) is not uncommon, dissemination to the gallbladder or prostate is very rare. We present 1 case of RCC with synchronous metastasis to the gallbladder and 1 case of RCC with metachronous metastasis to the prostate. These cases illustrate the propensity of RCC for unpredictable presentation and unusual sites of metastases. The first case also illustrates the benefit of adjuvant nephrectomy with excision of a solitary metastasis. Patterns of RCC metastases and flow cytometric analysis of RCC are discussed.
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              Metastatic carcinoma of the gallbladder from renal cancer presenting as intraluminal polypoid mass.

              A Iyama, H Satoh, S Harada … (1991)
              We report a rare case of secondary involvement of the gallbladder by metastatic renal cell carcinoma. A 71-year-old man was diagnosed as having a polypoid mass within the gallbladder when he underwent right nephrectomy for a renal cell carcinoma. A preoperative diagnosis of simultaneous carcinoma of the gallbladder was made, and extended cholecystectomy with regional lymphadenectomy was performed five months after the initial operation. Postoperative histological examination of the polypoid mass within the gallbladder and a pancreatic mass excised during the second surgery revealed these resected tumors to be identical to the clear cell type of renal cell carcinoma. We feel that this case presents synchronous involvement of the gallbladder and pancreas by metastatic renal cell carcinoma of the right kidney.
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                Author and article information

                Journal
                Journal ID (nlm-ta): Case Rep Oncol
                Journal ID (publisher-id): CRO
                Title: Case Reports in Oncology
                Publisher: S. Karger AG (Allschwilerstrasse 10, P.O. Box · Postfach · Case postale, CH–4009, Basel, Switzerland · Schweiz · Suisse, Phone: +41 61 306 11 11, Fax: +41 61 306 12 34, karger@karger.ch )
                ISSN (Electronic): 1662-6575
                Publication date Collection: Jan-Apr 2010
                Publication date (Electronic): 29 January 2010
                Publication date PMC-release: 29 January 2010
                Volume: 3
                Issue: 1
                Pages: 30-34
                Affiliations
                [1] aDepartment of Urology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
                [2] bDepartment of Pathology, Yokohama City University Hospital, Yokohama, Japan
                Author notes
                *Takashi Kawahara, MD, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004 (Japan), Tel. +81 45 787 2679, Fax +81 45 786 5775, E-Mail takashi_tk2001@ 123456yahoo.co.jp
                Article
                Publisher ID: cro0003-0030
                DOI: 10.1159/000279308
                PMC ID: 2918839
                PubMed ID: 20740155
                SO-VID: 8ba594cc-be6c-4730-bd6b-5f2f1afbb493
                Copyright © Copyright © 2010 by S. Karger AG, Basel
                License:

                This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License ( http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.

                History
                Page count
                Figures: 3, References: 12, Pages: 5
                Categories
                Subject: Published: January 2010

                ScienceOpen disciplines: Oncology & Radiotherapy
                Keywords: sunitinib,gallbladder metastasis,renal cell carcinoma
                Data availability:
                ScienceOpen disciplines: Oncology & Radiotherapy
                Keywords: sunitinib, gallbladder metastasis, renal cell carcinoma

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