Gallbladder Metastasis from Renal Cell Carcinoma

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Abstract

A 73-year-old female was operated with radical nephrectomy and cholecystectomy for renal cell carcinoma and suspected gallstones after 9 courses of sunitinib treatment. Gallbladder specimen showed gallbladder metastasis originating from the renal cell carcinoma. Gallbladder metastasis from renal cell carcinoma is rare. Here, we discuss a case of gallbladder metastasis from renal cell carcinoma.

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Most cited references 16

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The spread of tumors in the human body

RA Willis, R. WILLIS, R. WILLIS … (1952)

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Renal cell carcinoma metastatic to the gallbladder or prostate: two case reports.

Gwendalyn D. King, Maria Centeno, M F Sarosdy … (1995)

Although metastatic renal cell carcinoma (RCC) is not uncommon, dissemination to the gallbladder or prostate is very rare. We present 1 case of RCC with synchronous metastasis to the gallbladder and 1 case of RCC with metachronous metastasis to the prostate. These cases illustrate the propensity of RCC for unpredictable presentation and unusual sites of metastases. The first case also illustrates the benefit of adjuvant nephrectomy with excision of a solitary metastasis. Patterns of RCC metastases and flow cytometric analysis of RCC are discussed.

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Metastatic carcinoma of the gallbladder from renal cancer presenting as intraluminal polypoid mass.

A Iyama, H Satoh, S Harada … (1991)

We report a rare case of secondary involvement of the gallbladder by metastatic renal cell carcinoma. A 71-year-old man was diagnosed as having a polypoid mass within the gallbladder when he underwent right nephrectomy for a renal cell carcinoma. A preoperative diagnosis of simultaneous carcinoma of the gallbladder was made, and extended cholecystectomy with regional lymphadenectomy was performed five months after the initial operation. Postoperative histological examination of the polypoid mass within the gallbladder and a pancreatic mass excised during the second surgery revealed these resected tumors to be identical to the clear cell type of renal cell carcinoma. We feel that this case presents synchronous involvement of the gallbladder and pancreas by metastatic renal cell carcinoma of the right kidney.

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Journal

Journal ID (publisher-id): CRO

Journal ID (pmc): CRO

Journal ID (doi): 10.1159/issn.1662-6575

Title: Case Reports in Oncology

Publisher: S. Karger AG

ISSN (Electronic): 1662-6575

Publication date Subscription-year: 2010

Publication date Collection: January – April 2010

Publication date (Electronic): 29 January 2010

Volume: 3

Issue: 1

Pages: 30-34

Affiliations

^aDepartment of Urology, Yokohama City University Graduate School of Medicine, and ^bDepartment of Pathology, Yokohama City University Hospital, Yokohama, Japan

Article

Publisher ID: 279308 Pmcid ID: PMC2918839 Other ID: Case Rep Oncol 2010;3:30–34

DOI: 10.1159/000279308

PMC ID: PMC2918839

PubMed ID: 20740155

SO-VID: 8ba594cc-be6c-4730-bd6b-5f2f1afbb493

License:

Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) ( http://www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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Abstract

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Karger: Oncology

Most cited references 16

The spread of tumors in the human body

Renal cell carcinoma metastatic to the gallbladder or prostate: two case reports.

Metastatic carcinoma of the gallbladder from renal cancer presenting as intraluminal polypoid mass.

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