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      Low-methoxyl lemon pectin attenuates inflammatory responses and improves intestinal barrier integrity in caerulein-induced experimental acute pancreatitis.

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          Abstract

          Acute pancreatitis (AP) is a common clinical acute abdominal disease. The intestinal injury associated with AP will aggravate the condition retroactively. This study investigates whether the low-methoxyl pectin (LMP) isolated from lemon could attenuate AP and associated intestinal injury.

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          Author and article information

          Journal
          Mol Nutr Food Res
          Molecular nutrition & food research
          Wiley-Blackwell
          1613-4133
          1613-4125
          Apr 2017
          : 61
          : 4
          Affiliations
          [1 ] State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, P. R. China.
          [2 ] Division of Gastroenterology and Hepatology, Digestive Disease Institute, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, P. R. China.
          [3 ] Division of Medical Biology, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
          [4 ] Jiangnan University School of Medicine, Wuxi, P. R. China.
          Article
          10.1002/mnfr.201600885
          27921358
          88dbe4ad-7bc5-48f8-96c5-d9e7b2ad1357
          History

          Cytokines,Inflammation,Intestinal barrier function,Low-methoxyl lemon pectin,Short chain fatty acids,Tight junction

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