Risk of Clostridium difficile infection with acid suppressing drugs and antibiotics: meta-analysis.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Several studies have raised concern regarding the possible association between proton-pump inhibitors (PPIs) and Clostridium difficile infection (CDI). We aimed to perform a systematic review of incident and recurrent CDI in PPI users, and to evaluate the relative impact of concurrent antibiotic use, or switching acid suppression to histamine-2-receptor antagonists (H2RAs).

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Am. J. Gastroenterol.

Title: The American journal of gastroenterology

Publisher: Springer Nature America, Inc

ISSN (Electronic): 1572-0241

ISSN (Print): 0002-9270

Publication date (Electronic): Jul 2012

Volume: 107

Issue: 7

Affiliations

[1 ] Norwich Medical School, University of East Anglia, Norwich, UK.

Article

Publisher Item ID: ajg2012108

DOI: 10.1038/ajg.2012.108

PubMed ID: 22525304

SO-VID: 884674dd-701c-4576-8bdb-ffc3d1516198

History

Data availability:

Comments

Comment on this article

scite_

Smart Citations

Citing PublicationsSupportingMentioningContrasting

View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.