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      Lens nucleus dislocation in hypermature cataract: Case report and literature review

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          Introduction:

          Hypermature cataract is a form of late-stage cataract progression that can lead to a variety of complications. Spontaneous capsular rupture with lens nucleus displacement in hypermature cataracts has rarely been reported. We describe 2 cases of spontaneous dislocation of the lens nucleus in a hypermature cataract and perform a review of the literature on this complication.

          Patient Concerns:

          We report 2 rural men aged 50 and 76 years with deteriorating vision.

          Diagnosis:

          The final diagnosis was senile hypermature cataract with dislocation of the lens nucleus in both patients and secondary glaucoma for the second patient.

          Interventions and Outcomes:

          During admission, both patients complained of deteriorating vision. Slit-lamp examination showed lens nucleus dislocation into the anterior chamber. The 50-year-old patient exhibited a residual lens capsule and a turbid cortex, with a normal anterior chamber and intraocular pressure. The 76-year-old patient presented a shrunken and ruptured capsule and no cortex in the pupillary area, mild inflammation in the anterior chamber, and high intraocular pressure. Both patients underwent intracapsular cataract extraction combined with anterior vitrectomy and achieved good postoperative recovery.

          Conclusion:

          Lens nucleus dislocation in hypermature cataracts can be seen in clinical practice, particularly in underdeveloped areas. Early recognition and surgery can improve vision.

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          Most cited references18

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          Cataracts.

          An estimated 95 million people worldwide are affected by cataract. Cataract still remains the leading cause of blindness in middle-income and low-income countries. With the advancement of surgical technology and techniques, cataract surgery has evolved to small-incisional surgery with rapid visual recovery, good visual outcomes, and minimal complications in most patients. With the development of advanced technology in intraocular lenses, the combined treatment of cataract and astigmatism or presbyopia, or both, is possible. Paediatric cataracts have a different pathogenesis, surgical concerns, and postoperative clinical course from those of age-related cataracts, and the visual outcome is multifactorial and dependent on postoperative visual rehabilitation. New developments in cataract surgery will continue to improve the visual, anatomical, and patient-reported outcomes. Future work should focus on promoting the accessibility and quality of cataract surgery in developing countries.
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            Cat-Map: putting cataract on the map

            Lens opacities, or cataract(s), may be inherited as a classic Mendelian disorder usually with early-onset or, more commonly, acquired with age as a multi-factorial or complex trait. Many genetic forms of cataract have been described in mice and other animal models. Considerable progress has been made in mapping and identifying the genes and mutations responsible for inherited forms of cataract, and genetic determinants of age-related cataract are beginning to be discovered. To provide a convenient and accurate summary of current information focused on the increasing genetic complexity of Mendelian and age-related cataract we have created an online chromosome map and reference database for cataract in humans and mice (Cat-Map).
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              Cataract surgery in developing countries.

              To review the previous year's literature related to cataract surgery in developing countries and to provide fast, up-to-date information to the scientific world. Cataract is the leading cause of blindness, especially in developing countries. The prevalence of cataract increases with the aging population. Although cataract surgery is the most cost-effective intervention, its delivery in developing countries has many issues and challenges. A paradigm shift has occurred in the surgical techniques used for delivering cataract services and the outcomes have been positive in some countries compared to the scenario a decade ago. However, in some parts of Africa, it still continues to be a challenge. Apart from this, the issues related to ongoing supply of consumables and human resources continue to be a challenge in these countries. Although manual small incision cataract surgery is the most cost-effective intervention, there are other issues related to the delivery of services in developing countries. We need to plan a comprehensive strategy to deliver the services in developing countries if we want to achieve our goal of VISION 2020.
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                Author and article information

                Contributors
                Journal
                Medicine (Baltimore)
                Medicine (Baltimore)
                MD
                Medicine
                Lippincott Williams & Wilkins (Hagerstown, MD )
                0025-7974
                1536-5964
                02 September 2022
                02 September 2022
                : 101
                : 35
                : e30428
                Affiliations
                [a ] Kashgar Hospital Affiliated to Sun Yat-sen University, Xinjiang, China
                [b ] State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China
                [c ] Department of Ophthalmology, the First People’s Hospital of Kashi, Xinjiang, China.
                Author notes
                *Correspondence: Aizezi Wumaier, Kashgar Hospital Affiliated to Sun Yat-sen University, The First People’s Hospital of Kashi, No.120 Yingbin Avenue, Kashi, Xinjiang 844000, China (e-mail: azzksrmyy@ 123456163.com ).
                Author information
                https://orcid.org/0000-0001-9718-4923
                Article
                00024
                10.1097/MD.0000000000030428
                9439833
                823cd5cc-d07f-4cfb-8995-d0e66bc6ceda
                Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

                This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 20 April 2022
                : 6 June 2022
                : 27 July 2022
                Categories
                Research Article
                Clinical Case Report
                Custom metadata
                TRUE

                case report,ectopia lentis,intracapsular cataract extraction,literature review,morgagnian cataract

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