Corrigendum: Electroacupuncture-induced activation of GABAergic system alleviates airway inflammation in asthma model by suppressing TLR4/MyD88/NF-κB signaling pathway

Abstract

There are some errors in the article "Electroacupuncture-induced activation of GABAergic system alleviates airway inflammation in asthma model by suppressing TLR4/MyD88/NF-κB signaling pathway" which appeared in vol.136, issue 4, page 451–460 of Chinese Medical Journal.[1] First, the sentence in the Study design should be modified to "The level of GABA, the expressions of GABAAR, and TLR4/MyD88/NF-κB signaling pathway were assessed using Western blot and histological staining". Second, the drug concentration in the Establishment of the experimental animal model of asthma is wrong, the correct one is "OVA (Sigma Aldrich, Louis, MO, USA) and aluminum hydroxide (Al(OH)3; Sigma Aldrich) were prepared in concentrations of 250 μg/mL and 10 mg/mL, respectively". Third, there are four icon mistakes in Results, and the correct sentences should be submitted as following: "Inflammatory infiltration was significantly reduced in OVA + EA group compared with the OVA group (inflammation score 3.00 [3.00–3.25] vs. 5.00 [4.00–5.00], P = 0.010) [Figure 3A, C]", "In contrast to the OVA group, goblet cells were significantly reduced in the OVA + EA group (PAS score 4.00 [3.00–4.00] vs. 1.50 [1.00–2.00], P = 0.002) [Figure 3B, D]", "After inhibition of GABAAR, the OVA + EA + antagonist group showed more severe infiltration of inflammatory cells in alveoli, congestion of blood capillaries, and thickening of alveolar septa than in the OVA + EA group (inflammation score 4.50 [4.00–5.00] vs. 3.00 [3.00–3.25], P = 0.038) [Figures 3A, C]", "The PAS scores in the OVA + EA + antagonist group were significantly greater than those in the OVA + EA group (PAS score 3.00 [2.75–3.25] vs. 1.50 [1.00–2.00], P = 0.047) [Figures 3B, D]". The errors do not affect the results and conclusions of the article.