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      Alcoholism and homicide with respect to the classification systems of Lesch and Cloninger.

      Alcohol and Alcoholism (Oxford, Oxfordshire)
      Adult, Alcoholism, classification, epidemiology, psychology, Anxiety Disorders, Comorbidity, Cross-Sectional Studies, Cyclothymic Disorder, Ethanol, blood, Expert Testimony, legislation & jurisprudence, Female, Germany, Homicide, statistics & numerical data, Humans, Insanity Defense, Male, Middle Aged, Norepinephrine, Risk Factors, Statistics as Topic, Violence

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          Abstract

          Worldwide criminal statistics show a disproportionately high incidence of violent offences committed under the influence of alcohol. A psychopathological subtyping of alcohol dependence in offenders who committed homicide has mainly been related to impulsive and dissocial personalities up to now. In an investigation on 48 alcohol-dependent offenders who committed homicide, a subtyping according to the multidimensional classification systems of Lesch and Cloninger has now been conducted for the first time. In Lesch's classification, there was a high incidence of homicides committed by type II and type III subjects with the comorbidity anxiety and cyclothymia. While type III offenders were more often repeat offenders, there was a remarkably high rate of first offenders among type II subjects (Chi-squared test; chi(2) = 30.0, df = 3, P < 0.001). With respect to Lesch's typology, the blood alcohol concentrations did differ significantly in the group of offenders (Kruskal-Wallis, chi(2) = 18.3, df = 3, P < 0.001), whereas the blood alcohol concentration of type II offenders at the time of offence was significantly lower than in type III offenders (Mann-Whitney-U, Z = -3.47; P = 0.001). Regarding to the Cloninger's typology, no significant differences in the aforementioned parameters could be found. An excessive noradrenergic reaction of anxiety offenders with initial withdrawal is discussed as a possible explanatory model.

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