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      Fecal microbiota transplant for treatment of Clostridium difficile infection in immunocompromised patients.

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          Abstract

          Patients who are immunocompromised (IC) are at increased risk of Clostridium difficile infection (CDI), which has increased to epidemic proportions over the past decade. Fecal microbiota transplantation (FMT) appears effective for the treatment of CDI, although there is concern that IC patients may be at increased risk of having adverse events (AEs) related to FMT. This study describes the multicenter experience of FMT in IC patients.

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          Author and article information

          Journal
          Am. J. Gastroenterol.
          The American journal of gastroenterology
          1572-0241
          0002-9270
          Jul 2014
          : 109
          : 7
          Affiliations
          [1 ] Division of Gastroenterology, Brown Alpert Medical School, Women's Medicine Collaborative, Alpert Medical School of Brown University, Providence, Rhode Island, USA.
          [2 ] Indiana University School of Medicine, Indianapolis, Indiana, USA.
          [3 ] University of Minnesota Medical School, Minneapolis, Minnesota, USA.
          [4 ] University of Washington School of Medicine, Seattle, Washington, USA.
          [5 ] Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA.
          [6 ] Lahey Clinic Hospital and Medical Center, Tufts University School of Medicine, Burlington, Massachusetts, USA.
          [7 ] Centre for Digestive Diseases, Five Dock, Sydney, New South Wales, Australia.
          [8 ] Northern California Gastroenterology Consultants, Inc., Oakland, California, USA.
          [9 ] California Pacific Medical Center, San Francisco, California, USA.
          [10 ] Virginia Mason Medical Center, Seattle, Washington, USA.
          [11 ] Massachusetts General Hospital and Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
          [12 ] University of Alberta, Edmonton, Alberta, Canada.
          [13 ] University of Michigan, Ann Arbor, Michigan, USA.
          [14 ] Integris Baptist Medical Center, Oklahoma, Oklahoma, USA.
          [15 ] Ochsner Clinic Foundation, New Orleans, Louisiana, USA.
          [16 ] Seattle Children's Hospital, Seattle, Washington, USA.
          Article
          ajg2014133
          10.1038/ajg.2014.133
          24890442
          7ada092e-60d4-4fb4-92fa-7ec7d9e25685
          History

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