Nanoparticles: A Broad‐Spectrum ROS‐Eliminating Material for Prevention of Inflammation and Drug‐Induced Organ Toxicity (Adv. Sci. 10/2018)

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Abstract

Uncontrolled inflammation contributes to the pathogenesis of numerous diseases. Scavenging of reactive oxygen species (ROS) is promising for treatment of inflammatory diseases. To circumvent current limitations, in article number https://doi.org/10.1002/advs.201800781, Jianxiang Zhang and co‐workers report a material with broad‐spectrum ROS‐eliminating capability. A nanotherapy derived from this bioactive material shows superior efficacies in different mouse models of inflammation and oxidative stress injury.

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Author and article information

Journal

Journal ID (nlm-ta): Adv Sci (Weinh)

Journal ID (iso-abbrev): Adv Sci (Weinh)

Journal ID (doi): 10.1002/(ISSN)2198-3844

Journal ID (publisher-id): ADVS

Title: Advanced Science

Publisher: John Wiley and Sons Inc. (Hoboken )

ISSN (Electronic): 2198-3844

Publication date (Electronic): 17 October 2018

Publication date Collection: October 2018

Volume: 5

Issue: 10 ( doiID: 10.1002/advs.v5.10 )

Electronic Location Identifier: 1870065

Affiliations

[ ¹ ] Department of Pharmaceutics College of Pharmacy Third Military Medical University Chongqing 400038 China

[ ² ] Department of Cardiology Southwest Hospital Third Military Medical University Chongqing 400038 China

[ ³ ] Department of Cardiology Affiliated Hospital of North Sichuan Medical College Nanchong 637000 Sichuan Province China

[ ⁴ ] Department of Neurosurgery Renmin Hospital of Wuhan University Wuhan 430060 China

Article

Publisher ID: ADVS201870065

DOI: 10.1002/advs.201870065

PMC ID: 6193161

SO-VID: 78f30ac5-4de9-486f-8ce4-5ee30a094232

License:

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

History

Page count

Figures: 1, Tables: 0, Pages: 1, Words: 201

Custom metadata

source-schema-version-number 2.0

component-id advs201870065

cover-date October 2018

details-of-publishers-convertor Converter:WILEY_ML3GV2_TO_NLMPMC version:version=5.5.0.1 mode:remove_FC converted:18.10.2018

Keywords: antioxidants,inflammation,nanoparticles,reactive oxygen species,targeted therapy

Data availability:

Keywords: antioxidants, inflammation, nanoparticles, reactive oxygen species, targeted therapy

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