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Tertiary lymphoid structures in human lung cancers, a new driver of antitumor immune responses
other
Jérémy Goc
1
,
2
,
3 ,
Wolf-Herman Fridman
1
,
2
,
3 ,
Scott A Hammond
4 ,
Catherine Sautès-Fridman
1
,
2
,
3 ,
Marie-Caroline Dieu-Nosjean
1
,
2
,
3
,
*
29 May 2014
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Abstract
T-cell infiltrates are robust prognostic biomarkers in the majority of human cancers. However, the mechanisms that shape a protective T-cell response remain unclear. Our recent study implicates tertiary lymphoid structures in the shaping of an efficient and beneficial immune response in lung cancer patients.