Estimation of tissue osteopontin levels before and after different traditional therapeutic modalities in psoriatic patients.

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Abstract

Several lines of evidences support a major role for Th1 cells in psoriasis. Treatment of psoriasis with cyclosporine, methotrexate and psoralen plus ultraviolet A (PUVA) is associated with clinical improvement and decrease in epidermal hyperplasia. Osteopontin (OPN) exerts a T-helper type 1 (Th1) cytokine function, regulating inflammatory cell accumulation and function.

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Journal

Journal ID (iso-abbrev): J Eur Acad Dermatol Venereol

Title: Journal of the European Academy of Dermatology and Venereology : JEADV

Publisher: Wiley

ISSN (Electronic): 1468-3083

ISSN (Print): 0926-9959

Publication date (Electronic): Mar 2013

Volume: 27

Issue: 3

Affiliations

[1 ] Departments of Dermatology and Biochemistry, Faculty of Medicine, Cairo University, Cairo, Egypt.

Article

DOI: 10.1111/j.1468-3083.2011.04417.x

PubMed ID: 22221192

SO-VID: 7062df9e-8cd6-4573-a011-02c8731a3abb

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