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      Disc inflammation and Modic changes show an interaction effect on recovery after surgery for lumbar disc herniation.

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          Abstract

          To study the interaction between Modic changes (MC) and inflammation by macrophages in the disc, in relation to clinical symptoms before and after discectomy for lumbar disc herniation.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Eur Spine J
          Title: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
          Publisher: Springer Science and Business Media LLC
          ISSN (Electronic): 1432-0932
          ISSN (Print): 0940-6719
          Publication date (Electronic): Nov 2019
          Volume: 28
          Issue: 11
          Affiliations
          [1 ] Department of Neurosurgery, Leiden University Medical Center, Albinusdreef 2, 2300 RC, Leiden, The Netherlands. n.djuric@lumc.nl.
          [2 ] Department of Neurosurgery, Leiden University Medical Center, Albinusdreef 2, 2300 RC, Leiden, The Netherlands.
          [3 ] Department of Epidemiology, VU Medical Centre, Amsterdam, The Netherlands.
          [4 ] Department of Health Sciences, Faculty of Science, Amsterdam Movement Sciences Research Institute, Vrije Universiteit, Amsterdam, The Netherlands.
          [5 ] Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
          [6 ] Haaglanden Medical Centre, The Hague, The Netherlands.
          Article
          Publisher Item ID: 10.1007/s00586-019-06108-9
          DOI: 10.1007/s00586-019-06108-9
          PubMed ID: 31440895
          SO-VID: 6f72b7cd-08e7-4651-a052-d59289e3ccbf
          History

          Keywords: Inflammation,Macrophage,Modic type 2 changes,Roland disability questionnaire,Sciatica
          Data availability:
          Keywords: Inflammation, Macrophage, Modic type 2 changes, Roland disability questionnaire, Sciatica

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