Contributors
Damien Coté:
ORCID: http://orcid.org/0000-0002-4011-8965
Role: Formal analysisRole: ValidationRole: Writing – original draftRole: Writing –
review & editing
Alex Eustace: Role: SupervisionRole: Writing – original draftRole: Writing – review & editing
Sinead Toomey: Role: MethodologyRole: Writing – review & editing
Mattia Cremona: Role: MethodologyRole: Writing – review & editing
Malgorzata Milewska: Role: MethodologyRole: Writing – review & editing
Simon Furney: Role: MethodologyRole: Writing – review & editing
Aoife Carr: Role: MethodologyRole: Writing – review & editing
Joanna Fay: Role: MethodologyRole: Writing – review & editing
Elaine Kay: Role: MethodologyRole: Writing – review & editing
Susan Kennedy: Role: InvestigationRole: Writing – review & editing
John Crown: Role: InvestigationRole: Writing – review & editing
Bryan Hennessy: Role: InvestigationRole: SupervisionRole: Writing – review & editing
Stephen Madden: Role: SupervisionRole: Writing – review & editing
Elda Tagliabue: Role: Editor
Journal
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
2
August
2018
Publication date Collection: 2018
Volume: 13
Issue: 8
Electronic Location Identifier: e0200996
Affiliations
[1
]
Royal College of Surgeons in Ireland, Data Science Centre, Dublin, Ireland
[2
]
Dublin City University, National Institute for Cellular Biotechnology, Molecular Therapeutics
for Cancer in Ireland, Dublin, Ireland
[3
]
Royal College of Surgeons in Ireland, Department of Molecular Medicine, Medical Oncology
Group, Dublin, Ireland
[4
]
Royal College of Surgeons in Ireland, Department of Physiology and Medical Physics,
Dublin, Ireland
[5
]
Royal College of Surgeons in Ireland, Department of Pathology, Dublin, Ireland
[6
]
St Vincent’s University Hospital, Medical Oncology, Dublin, Ireland
[7
]
Beaumont Hospital, Department of Medical Oncology, Dublin, Ireland
Fondazione IRCCS Istituto Nazionale dei Tumori, ITALY
Author notes
Competing Interests: The TCHL clinical study was sponsored by Cancer Trials Ireland (formerly known as
the Irish Clinical Oncology Research Group [ICORG]), which received funding from GlaxoSmithKline.
There are no patents, products in development or marketed products to declare. This
does not alter our adherence to all the PLOS ONE policies on sharing data and materials.
‡ These authors also contributed equally to this work.
Author information
Article
Publisher ID:
PONE-D-18-04727
DOI: 10.1371/journal.pone.0200996
PMC ID: 6071997
PubMed ID: 30071039
SO-VID: 6f193238-682e-47c9-93b2-dc223c32c598
Copyright © © 2018 Coté et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 12
February
2018
Date
accepted
: 6
July
2018
Page count
Figures: 5,
Tables: 6,
Pages: 17
Funding
Funded by: funder-id http://dx.doi.org/10.13039/501100001593, Irish Cancer Society;
Award ID: CCRC13GAL
Funded by: funder-id http://dx.doi.org/10.13039/100010414, Health Research Board;
Award ID: HRA/POR2012/054
Funded by: North East Cancer Research and Education Trust
Funded by: funder-id http://dx.doi.org/10.13039/501100001602, Science Foundation Ireland;
Award ID: 08-SRC-B1410
The TCHL clinical study was sponsored by Cancer Trials Ireland (formerly known as
the Irish Clinical Oncology Research Group [ICORG]), which received funding from GlaxoSmithKline.
This work was supported by the Irish Cancer Society Collaborative Cancer Research
Centre under BREAST-PREDICT grant CCRC13GAL (
www.breastpredict.com), the Health Research Board (HRA/POR2012/054), the North East Cancer Research and
Education Trust, and the Science Foundation Ireland-funded Molecular Therapeutics
for Cancer Ireland (08-SRC-B1410). The funders had no role in study design, data collection
and analysis, decision to publish, or preparation of the manuscript.The funders had
no role in study design, data collection and analysis, decision to publish, or preparation
of the manuscript.
Categories
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancer Treatment
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancers and Neoplasms
Subject:
Breast Tumors
Subject:
Breast Cancer
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Chemical Elements
Subject:
Platinum
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Molecular Genetics
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Genetics
Subject:
Computer and Information Sciences
Subject:
Artificial Intelligence
Subject:
Machine Learning
Subject:
Support Vector Machines
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Protein Domains
Subject:
Medicine and Health Sciences
Subject:
Pharmaceutics
Subject:
Drug Therapy
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancer Risk Factors
Subject:
Genetic Causes of Cancer
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