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      Hypertension management in rural primary care facilities in Zambia: a mixed methods study

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          Abstract

          Background

          Improved primary health care is needed in developing countries to effectively manage the growing burden of hypertension. Our objective was to evaluate hypertension management in Zambian rural primary care clinics using process and outcome indicators to assess the screening, monitoring, treatment and control of high blood pressure.

          Methods

          Better Health Outcomes through Mentoring and Assessment (BHOMA) is a 5-year, randomized stepped-wedge trial of improved clinical service delivery underway in 46 rural Zambian clinics. Clinical data were collected as part of routine patient care from an electronic medical record system, and reviewed for site performance over time according to hypertension related indicators: screening (blood pressure measurement), management (recorded diagnosis, physical exam or urinalysis), treatment (on medication), and control. Quantitative data was used to develop guides for qualitative in-depth interviews, conducted with health care providers at a proportional sample of half (20) of clinics. Qualitative data was iteratively analyzed for thematic content.

          Results

          From January 2011 to December 2014, 318,380 visits to 46 primary care clinics by adults aged ≥ 25 years with blood pressure measurements were included. Blood pressure measurement at vital sign screening was initially high at 89.1% overall (range: 70.1–100%), but decreased to 62.1% (range: 0–100%) by 48 months after intervention start. The majority of hypertensive patients made only one visit to the clinics (57.8%). Out of 9022 patients with at least two visits with an elevated blood pressure, only 49.3% had a chart recorded hypertension diagnosis. Process indicators for monitoring hypertension were <10% and did not improve with time. In in-depth interviews, antihypertensive medication shortages were common, with 15/20 clinics reporting hydrochlorothiazide-amiloride stockouts. Principal challenges in hypertension management included 1) equipment and personnel shortages, 2) provider belief that multiple visits were needed before official management, 3) medication stock-outs, leading to improper prescriptions and 4) poor patient visit attendance.

          Conclusions

          Our findings suggest that numerous barriers stand in the way of hypertension diagnosis and management in Zambian primary health facilities. Future work should focus on performance indicator development and validation in low resource contexts, to facilitate regular and systematic data review to improve patient outcomes.

          Trial registration

          ClinicalTrials.gov, Identifier NCT01942278. Date of Registration: September 2013.

          Electronic supplementary material

          The online version of this article (doi:10.1186/s12913-017-2063-0) contains supplementary material, which is available to authorized users.

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          Most cited references18

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          Global Status Report on Noncommunicable Diseases 2010

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            Social epidemiology of hypertension in middle-income countries: determinants of prevalence, diagnosis, treatment, and control in the WHO SAGE study.

            Large-scale hypertension screening campaigns have been recommended for middle-income countries. We sought to identify sociodemographic predictors of hypertension prevalence, diagnosis, treatment, and control among middle-income countries. We analyzed data from 47 443 adults in all 6 middle-income countries (China, Ghana, India, Mexico, Russia, and South Africa) sampled in nationally representative household assessments from 2007 to 2010 as part of the World Health Organization Study on Global Aging and Adult Health. We estimated regression models accounting for age, sex, urban/rural location, nutrition, and obesity, as well as hypothesized covariates of healthcare access, such as income and insurance. Hypertension prevalence varied from 23% (India) to 52% (Russia), with between 30% (Russia) and 83% (Ghana) of hypertensives undiagnosed before the survey and between 35% (Russia) and 87% (Ghana) untreated. Although the risk of hypertension significantly increased with age (odds ratio, 4.6; 95% confidence interval, 3.0-7.1; among aged, 60-79 versus <40 years), the risk of being undiagnosed or untreated fell significantly with age. Obesity was a significant correlate to hypertension (odds ratio, 3.7; 95% confidence interval, 2.1-6.8 for obese versus normal weight), and was prevalent even among the lowest income quintile (13% obesity). Insurance status and income also emerged as significant correlates to diagnosis and treatment probability, respectively. More than 90% of hypertension cases were uncontrolled, with men having 3 times the odds as women of being uncontrolled. Overall, the social epidemiology of hypertension in middle-income countries seems to be correlated to increasing obesity prevalence, and hypertension control rates are particularly low for adult men across distinct cultures.
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              30 years after Alma-Ata: has primary health care worked in countries?

              We assessed progress for primary health care in countries since Alma-Ata. First we analysed life expectancy relative to national income and HIV prevalence to identify overachieving and underachieving countries. Then we focused on the 30 low-income and middle-income countries with the highest average yearly reduction of mortality among children less than 5 years of age, describing coverage and equity of primary health care as well as non-health sector actions. These 30 countries have scaled up selective primary health care (eg, immunisation, family planning), and 14 have progressed to comprehensive primary health care, marked by high coverage of skilled attendance at birth. Good governance and progress in non-health sectors are seen in almost all of the 14 countries identified with a comprehensive primary health care system. However, these 30 countries include those that are making progress despite very low income per person, political instability, and high HIV/AIDS prevalence. Thailand has the highest average yearly reduction in mortality among children less than 5 years of age (8.5%) and has achieved universal coverage of immunisation and skilled birth attendance, with low inequity. Lessons learned from all these countries include the need for a nationally agreed package of prioritised and phased primary health care that all stakeholders are committed to implementing, attention to district management systems, and consistent investment in primary health-care extension workers linked to the health system. More detailed analysis and evaluation within and across countries would be invaluable in guiding investments for primary health care, and expediting progress towards the Millennium Development Goals and "health for all".
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                Author and article information

                Contributors
                lilyyan@alumni.stanford.edu
                cindy.chirwa@cidrz.org
                benjamin_chi@med.unc.edu
                samuel.bosomprah@cidrz.org
                ntazana.sindano@cidrz.org
                moses.mwanza@cidrz.org
                dennis_musatwe@yahoo.com
                mary.mulenga@cidrz.org
                roma.chilengi@cidrz.org
                Journal
                BMC Health Serv Res
                BMC Health Serv Res
                BMC Health Services Research
                BioMed Central (London )
                1472-6963
                3 February 2017
                3 February 2017
                2017
                : 17
                : 111
                Affiliations
                [1 ]Primary Care and Health Systems Department, Center for Infectious Disease Research Zambia, Lusaka, Zambia
                [2 ]ISNI 0000000419368956, GRID grid.168010.e, , Stanford University School of Medicine, ; Stanford, CA USA
                [3 ]ISNI 0000000122483208, GRID grid.10698.36, Department of Obstetrics and Gynecology, , University of North Carolina School of Medicine, ; Chapel Hill, NC USA
                [4 ]ISNI 0000 0004 1937 1485, GRID grid.8652.9, Department of Biostatistics, , School of Public Health, University of Ghana, ; Accra, Ghana
                Article
                2063
                10.1186/s12913-017-2063-0
                5292001
                28158981
                687238fa-a7d2-48df-a2ec-3abcf07ababa
                © The Author(s). 2017

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 8 October 2015
                : 28 January 2017
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/100000862, Doris Duke Charitable Foundation;
                Award ID: 2009060
                Award Recipient :
                Funded by: Comic Relief
                Award ID: 146781
                Award Recipient :
                Funded by: FundRef http://dx.doi.org/10.13039/100000862, Doris Duke Charitable Foundation;
                Categories
                Research Article
                Custom metadata
                © The Author(s) 2017

                Health & Social care
                hypertension,zambia,mixed methods,antihypertensive medication,performance indicators,quality improvement

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