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      Diagnosis of osteoporosis in dental patients

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          Abstract

          Osteoporosis is a severe skeletal disease that leads to bone fractures, even disability, if it remains undetected. However, osteoporosis remains frequently unnoticed until a fracture occurs. It is possible for dental practitioners to screen patients at risk of osteoporosis and refer them for an osteoporosis evaluation. Screening can be achieved mainly through dental radiographs and especially panoramic x-rays, where several radiographic indices, such as Mandibular Cortical Width (MCW), Mandibular Cortical Index (MCI), Gonial Index (GI), Antigonial Index (AI), Panoramic Mandibular Index (PMI) and alveolar crest resorption degree (M/M ratio) can be assessed. Furthermore, patients with osteoporosis develop changes in the trabecular bone of their jaws and those alternations can be detected by dentists through periapical and panoramic x-rays. Moreover, periodontitis, which is a major reason for tooth loss, deteriorates when the patient also suffers from osteoporosis. Dentists can thus screen their patients who are possibly unaware of their osteoporosis, and refer them further for dual-energy X-ray absorptiometry (DXA) examination. However, all the above indices are merely indicative of low skeletal bone mineral density and the dentist must always take into account the medical history and clinical risk factors of osteoporosis before further referring to an osteoporosis specialist.

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          Most cited references41

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          Mandibular radiomorphometric indices in the diagnosis of reduced skeletal bone mineral density.

          Diagnosis of osteoporosis allows the delivery of preventive and therapeutic intervention and is usually achieved using bone densitometric techniques. One referral criterion for densitometry is osteopenia on radiographs. The aim of this study was to measure the validity of mandibular cortical indices measured on panoramic radiographs in the diagnosis of reduced skeletal bone density. Seventy-four women underwent bone densitometry of the femoral neck, lumbar spine and the forearm. Fifty-five patients (74%) were classified as having a reduced bone density (T-score < or = -1). Twenty-seven patients had a T-score of < -2.5 observed at one or more of the three measurement sites. A panoramic radiograph was taken of each patient and two observers made measurements of cortical thickness at the mental foramen (mental index, MI), antegonion (antegonial index, AI) and gonion (gonial index, GI) regions. Logistic regression and receiver operating characteristic (ROC) curve analyses were used to measure the validity of cortical indices in the diagnosis of reduced bone mineral density. Only MI contributed significantly to a diagnosis of low skeletal bone mineral density (T-score < or = -1). The 95% limits of agreement between observers in measurement of MI were 1.32 to +1.32 mm. When data for both observers were combined, the area under the ROC curve was 0.733 (SE = 0.072; 95% confidence interval = 0.618 to 0.83), indicating moderate accuracy. A diagnostic threshold for MI of 3 mm (or less) is suggested as the most appropriate threshold for referral for bone densitometry. However, the study provided only limited support for the use of panoramic radiomorphometric indices in diagnosing low skeletal bone mineral density. They might, questionably, be used as part of a method of osteoporosis risk assessment.
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            Alterations of the trabecular pattern of the jaws in patients with osteoporosis.

            The purpose of this study was to determine whether the morphologic features of the trabecular bones of the maxilla and mandible differ between patients with osteoporosis and normal controls. Periapical radiographs, obtained from dentists of 11 patients with osteoporosis and 12 control subjects, were digitized at 600 dpi. A custom computer program measured morphologic features of the trabecular architecture. The mean values for each feature were determined for the osteoporotic and control groups and compared by anatomic site. Twenty-four morphologic features of the trabeculae and marrow regions were examined in each anatomical site. A principal components analysis summarized these predictors to four. The Hotelling T (2) test found that patients with osteoporosis had significantly altered morphologic pattern in the anterior maxilla (P =.019) and the posterior mandible (P =.013) in comparison with the controls. A classification tree analysis separated all subjects into 2 groups with 92% accuracy. The data support the hypothesis that patients with osteoporosis have an altered trabecular pattern in the jaws in comparison with normal subjects.
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              Diagnosing osteoporosis by using dental panoramic radiographs: the OSTEODENT project.

              Measurement of cortical thickness and subjective assessment of cortical porosity on panoramic radiographs are methods previously reported for diagnosing osteoporosis. The aims of this study were to determine the relative efficacy of the mandibular cortical index and cortical width in detecting osteoporosis, both alone and in combination, and to determine the optimal cortical width threshold for referral for additional osteoporosis investigation. Six hundred seventy-one postmenopausal women 45 to 70 years of age were recruited for this study. They received dual energy x-ray absorptiometry (DXA) scans of the left hip and lumbar spine (L1 to L4), and dental panoramic radiographic examinations of the teeth and jaws. Three observers separately assessed the mandibular cortical width and porosity in the mental foramen region of the mandible. Cortical width was corrected for magnification errors. Chi-squared automatic interaction detection analysis (CHAID) software was used (SPSS AnswerTree, version 3.1, SPSS Inc., Chicago, IL). Chi-squared automatic interaction detection analysis showed that the cortical porosity was a poorer predictor of osteoporosis than mandibular cortical width. For the 3 observers, a mandibular cortical width of <3 mm provided diagnostic odds ratios of 6.51, 6.09, and 8.04. The test is therefore only recommended in triage screening of individuals by using radiographs made for purposes other than osteoporosis. When evaluating panoramic radiographs, only those patients with the thinnest mandibular cortices (i.e., <3 mm) should be referred for further osteoporosis investigation.
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                Author and article information

                Journal
                J Frailty Sarcopenia Falls
                J Frailty Sarcopenia Falls
                Journal of Frailty, Sarcopenia and Falls
                HYLONOME PUBLICATIONS (Greece )
                2459-4148
                June 2017
                01 June 2017
                : 2
                : 2
                : 21-27
                Affiliations
                [1] General Dentist
                Author notes
                Corresponding author: Theodora S. Tounta, 29 K.Varnali Street, N. Erythrea 14671, Athens, Greece E-mail: theodoratounta@ 123456gmail.com

                The author has no conflict of interest.

                Article
                JFSF-2-021
                10.22540/JFSF-02-021
                7155378
                32300679
                5e8942cd-f5c3-43d8-8372-1ca0c3c6dd85
                Copyright: © 2017 Hylonome Publications

                All published work is licensed under Creative Commons Attribution NonCommercial - ShareAlike 4.0 International

                History
                : 10 May 2017
                Categories
                Review Article

                osteoporosis,panoramic x-rays,mandibular cortex,periodontitis,tooth loss

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