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      Effects of dietary supplements on athletic performance in elite soccer players: a systematic review

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          ABSTRACT

          Dietary supplements are widely used among athletes, and soccer players are no exception. Nevertheless, evidence supporting the use of dietary supplements aiming to enhance performance in soccer is somewhat contradictory, scarce, or even nonexistent. Thus, the present study aimed to systematically review and synthesize the effects of dietary supplements on athletic performance (e.g. distance covered, sprinting, jump performance) in elite soccer players. Studies enrolling highly trained, elite, and world-class soccer players using dietary supplements were searched in MEDLINE/PubMed, Web of Science, Scopus, and EBSCO databases in June 2022. In total, 1043 studies were identified, and 18 met the eligibility criteria. The studies evaluated the impacts on athletic performance of several dietary supplements, including caffeine, creatine, protein, beverages with carbohydrates and electrolytes, tart cherry juice, nitrate-rich beetroot juice, sodium bicarbonate with minerals, yohimbine, and a proprietary nutraceutical blend. Caffeine supplementation in doses between 3 and 6 mg/kg of body mass may improve jump height and sprint ability, particularly in female players, but individual response to caffeine must be considered. Creatine may improve sprint, agility, and in female players, jump performance. Protein supplementation can improve sprint and jump performance between matches, especially if protein ingested from food is not up to recommendations. Beverages containing carbohydrates and electrolytes can be used as part of the strategies to achieve carbohydrate intake during training and match-days but used alone do not benefit athletic performance. Tart cherry juice might be useful for maintaining athletic performance after matches that produce higher force loss and exercise-induced muscle damage, although polyphenols from the diet might attenuate the effects of tart cherry supplementation. Nitrate-rich beetroot concentrate can attenuate performance decrease in the days following matches. Further investigation with sodium bicarbonate alone is necessary, as supplementation protocols with elite players included other substances. Finally, the available data does not support yohimbine supplementation or the use of Resurgex Plus® to improve athletic performance in elite soccer players. Still, more well-designed research with elite soccer players is needed to improve support and advice regarding the use of dietary supplements for athletic performance enhancement.

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          The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

          The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found. Over the past decade, advances in systematic review methodology and terminology have necessitated an update to the guideline. The PRISMA 2020 statement replaces the 2009 statement and includes new reporting guidance that reflects advances in methods to identify, select, appraise, and synthesise studies. The structure and presentation of the items have been modified to facilitate implementation. In this article, we present the PRISMA 2020 27-item checklist, an expanded checklist that details reporting recommendations for each item, the PRISMA 2020 abstract checklist, and the revised flow diagrams for original and updated reviews.
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            RoB 2: a revised tool for assessing risk of bias in randomised trials

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              Creatine and creatinine metabolism.

              The goal of this review is to present a comprehensive survey of the many intriguing facets of creatine (Cr) and creatinine metabolism, encompassing the pathways and regulation of Cr biosynthesis and degradation, species and tissue distribution of the enzymes and metabolites involved, and of the inherent implications for physiology and human pathology. Very recently, a series of new discoveries have been made that are bound to have distinguished implications for bioenergetics, physiology, human pathology, and clinical diagnosis and that suggest that deregulation of the creatine kinase (CK) system is associated with a variety of diseases. Disturbances of the CK system have been observed in muscle, brain, cardiac, and renal diseases as well as in cancer. On the other hand, Cr and Cr analogs such as cyclocreatine were found to have antitumor, antiviral, and antidiabetic effects and to protect tissues from hypoxic, ischemic, neurodegenerative, or muscle damage. Oral Cr ingestion is used in sports as an ergogenic aid, and some data suggest that Cr and creatinine may be precursors of food mutagens and uremic toxins. These findings are discussed in depth, the interrelationships are outlined, and all is put into a broader context to provide a more detailed understanding of the biological functions of Cr and of the CK system.
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                Author and article information

                Journal
                J Int Soc Sports Nutr
                J Int Soc Sports Nutr
                Journal of the International Society of Sports Nutrition
                Routledge
                1550-2783
                18 July 2023
                2023
                18 July 2023
                : 20
                : 1
                : 2236060
                Affiliations
                [a ]Portugal Football School, Portuguese Football Federation, FPF; , Oeiras, Portugal
                [b ]Faculty of Nutrition and Food Science of the University of Porto (FCNAUP); , Porto, Portugal
                [c ]NMS, FCM, Universidade NOVA de Lisboa; , CHRC, NOVA Medical School, Faculdade de Ciências Médicas, Lisboa, Portugal
                [d ]University of Porto; , Research Centre in Physical Activity, Health and Leisure, CIAFEL, Faculty of Sport, Porto, Portugal
                [e ]Laboratory for Integrative and Translational Research in Population Health (ITR); , Porto, Portugal
                [f ]Futebol Clube Do Porto SAD; , Porto, Portugal
                Author notes
                CONTACT Rodrigo Abreu rodrigo.abreu@ 123456fpf.pt Portugal Football School, Portuguese Football Federation; , Avenida das Seleções, Cruz Quebrada 1495-433, Portugal
                Author information
                https://orcid.org/0000-0001-5298-5268
                https://orcid.org/0000-0001-9575-9703
                https://orcid.org/0000-0002-8225-8667
                https://orcid.org/0000-0002-6103-6360
                https://orcid.org/0000-0002-9286-4716
                Article
                2236060
                10.1080/15502783.2023.2236060
                10355692
                37462346
                5a67be2e-7819-4ede-9feb-a762d7056d71
                © 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License ( http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

                History
                Page count
                Figures: 2, Tables: 1, References: 87, Pages: 1
                Categories
                Review Article
                Review Article

                Sports medicine
                football,nutrition,recovery,supplementation,ergogenic aids
                Sports medicine
                football, nutrition, recovery, supplementation, ergogenic aids

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