Transplantation of adipose-derived stem cells combined with collagen scaffolds restores ovarian function in a rat model of premature ovarian insufficiency.

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Abstract

Does the transplantation of adipose-derived stem cells (ADSCs) on soluble collagen scaffolds (collagen/ADSCs) have better therapeutic effect than transplantation of ADSCs alone, to treat premature ovarian insufficiency (POI) in a rat model induced by Tripterygium Glycosides (TG)?

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Journal

Journal ID (iso-abbrev): Hum. Reprod.

Title: Human reproduction (Oxford, England)

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 1460-2350

ISSN (Print): 0268-1161

Publication date (Electronic): May 2016

Volume: 31

Issue: 5

Affiliations

[1 ] Department of Obstetrics and Gynecology, Center for Reproductive Medicine, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing 210008, China.

[2 ] Department of Pathology, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing 210008, China.

[3 ] Department of Obstetrics and Gynecology, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing 210008, China.

[4 ] Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 3 Nanyitiao, Zhongguancun, Beijing 100190, China yalihu@nju.edu.cn jwdai@genetics.ac.cn.

[5 ] Department of Obstetrics and Gynecology, Center for Reproductive Medicine, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing 210008, China Department of Obstetrics and Gynecology, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing 210008, China yalihu@nju.edu.cn jwdai@genetics.ac.cn.

Article

Publisher Item ID: dew041

DOI: 10.1093/humrep/dew041

PubMed ID: 26965432

SO-VID: 59304b46-4c60-462a-b9da-f8c9313ab0eb

History

Keywords: ovary/estradiol,adipose-derived stem cells,tripterygium glycosides,premature ovarian insufficiency,soluble collagen scaffold

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Keywords: ovary/estradiol, adipose-derived stem cells, tripterygium glycosides, premature ovarian insufficiency, soluble collagen scaffold

Transplantation of adipose-derived stem cells combined with collagen scaffolds restores ovarian function in a rat model of premature ovarian insufficiency.

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Animal models of intrauterine growth restriction (IUGR)

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