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Thrombotic issues in transgender medicine: A review : Thrombotic issues in transgender medicine
January 17 2017
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Abstract
<p class="first" id="d15191945e90">Clinicians, including hematologists, are more frequently
encountering transgender
individuals in practice; however, most lack training on the management and complications
of transgender medicine. Hormonal therapy forms the backbone of medical interventions
for patients undergoing gender transition. While supplementing an individual's intrinsic
sex hormone is associated with a variety of hematologic complications including increased
rates of venous thrombosis, cardiovascular events, erthyrocytosis, and malignancy,
the risks of supplementing with opposing sex hormones are not well understood. Data
on the hematologic complications of these therapies are accumulating but remain limited,
and clinicians have little experience with their management. This review highlights
the current interventions available in transgender medicine and related potential
hematologic complications, and it suggests simple, evidence-based management going
forward. Am. J. Hematol. 92:204-208, 2017. © 2016 Wiley Periodicals, Inc.
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