Comparison of succinimidyl [(125)I]iodobenzoate with iodogen iodination methods to study pharmacokinetics and ADME of biotherapeutics.

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Abstract

To assess the application of succinimidyl iodobenzoate (SIB) iodination method in labeling biotherapeutics to study their pharmacokinetics (PK) and biodistribution.

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Journal

Journal ID (iso-abbrev): Pharm. Res.

Title: Pharmaceutical research

Publisher: Springer Nature America, Inc

ISSN (Electronic): 1573-904X

ISSN (Print): 0724-8741

Publication date (Electronic): Oct 2014

Volume: 31

Issue: 10

Affiliations

[1 ] Department of Clinical & Translational Imaging, Precision Medicine, Pfizer Inc, Cambridge, Massachusetts, 02139, USA.

Article

DOI: 10.1007/s11095-014-1378-3

PubMed ID: 24844406

SO-VID: 53555f3e-63cf-4f7f-8014-0dffbe86013e

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