In vitro selection of RNA molecules that bind specific ligands.

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Abstract

Subpopulations of RNA molecules that bind specifically to a variety of organic dyes have been isolated from a population of random sequence RNA molecules. Roughly one in 10(10) random sequence RNA molecules folds in such a way as to create a specific binding site for small ligands.

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PubMed ID:: 1697402

DOI:: 10.1038/346818a0

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In vitro selection of RNA molecules that bind specific ligands.

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