Comprehensive analysis of cuproptosis-related genes in prognosis, tumor microenvironment infiltration, and immunotherapy response in gastric cancer.

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Abstract

Cuproptosis is the most recently identified copper-dependent cell death form that influences tricarboxylic acid (TCA) cycle. However, the relationship between cuproptosis and clinical prognosis, tumor microenvironment infiltration (TME), and response to immunotherapy remains unclear.

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Journal

Journal ID (iso-abbrev): J Cancer Res Clin Oncol

Title: Journal of cancer research and clinical oncology

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1432-1335

ISSN (Print): 0171-5216

Publication date (Electronic): Jul 2023

Volume: 149

Issue: 8

Affiliations

[1 ] Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.

[2 ] Clinical Center and Key Lab of Intestinal and Colorectal Diseases of Hubei Province, Wuhan, 430071, China.

[3 ] Department of Gastroenterology, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi, 445000, China. xfcpff@163.com.

[4 ] Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. xhfangjun@163.com.

[5 ] Clinical Center and Key Lab of Intestinal and Colorectal Diseases of Hubei Province, Wuhan, 430071, China. xhfangjun@163.com.

[6 ] Department of Gastroenterology, Renmin Hospital of Huangmei County, Huanggang, 435500, China. xhfangjun@163.com.

[7 ] Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. 2020283030092@whu.edu.cn.

[8 ] Clinical Center and Key Lab of Intestinal and Colorectal Diseases of Hubei Province, Wuhan, 430071, China. 2020283030092@whu.edu.cn.

Article

Publisher Item ID: 10.1007/s00432-022-04474-4

DOI: 10.1007/s00432-022-04474-4

PubMed ID: 36462036

SO-VID: 4ee37c66-62b2-475a-b22d-a1246566c510

History

Keywords: Cuproptosis,Immunotherapy,Gastric cancer,Prognosis,Tumor microenvironment

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Keywords: Cuproptosis, Immunotherapy, Gastric cancer, Prognosis, Tumor microenvironment

Comprehensive analysis of cuproptosis-related genes in prognosis, tumor microenvironment infiltration, and immunotherapy response in gastric cancer.

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Karger: Oncology

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