Predictors of response to omalizumab and relapse in chronic spontaneous urticaria:
      a study of 470 patients

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Abstract

Chronic spontaneous urticaria (CSU) is defined as spontaneous occurrence of wheals and/or angioedema for ≥6 weeks. Omalizumab is a monoclonal anti-IgE antibody effective in refractory CSU, but its mechanism of action and markers predictive of response remain not completely defined.

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Author and article information

Contributors

A.V. Marzano: (View ORCID Profile)

G. Genovese: (View ORCID Profile)

Journal

Title: Journal of the European Academy of Dermatology and Venereology

Abbreviated Title: J Eur Acad Dermatol Venereol

Publisher: Wiley

ISSN (Print): 0926-9959

ISSN (Electronic): 1468-3083

Publication date Created: February 28 2019

Publication date Created: May 2019

Publication date (Electronic): December 07 2018

Publication date (Print): May 2019

Volume: 33

Issue: 5

Pages: 918-924

Affiliations

[1 ]UOC Dermatologia Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico Milan Italy

[2 ]Dipartimento di Fisiopatologia Medico‐Chirurgica e dei Trapianti Università degli Studi di Milano Milan Italy

[3 ]Dipartimento di Scienze Biomediche e Cliniche “L. Sacco” Università degli Studi di Milano Milan Italy

[4 ]Department of Medical Sciences Section of Dermatology University of Turin Turin Italy

[5 ]Department of Clinical and Experimental Medicine‐Respiratory Medicine & Allergy University of Catania Catania Italy

[6 ]Dermatology Unit Surgical, Medical and Dental Department of Morphological Sciences Related to Transplant, Oncology and Regenerative Medicine University of Modena and Reggio Emilia Modena Italy

[7 ]Clinical Dermatology Department of Biomedical, Surgical and Dental Sciences IRCCS Galeazzi Orthopaedic Institute University of Milan Milan Italy

[8 ]Dermatology Unit Department of Clinical and Molecular Sciences Polytechnic Marche University Ancona Italy

[9 ]Department of Medicine Section of Dermatology University of Verona Verona Italy

[10 ]Department of Biomedical Science and Human Oncology Section of Dermatology University of Bari Bari Italy

[11 ]Section of Clinical, Allergological and Venereological Dermatology Department of Medicine University of Perugia Perugia Italy

[12 ]Service of Occupational and Environmental Allergic Dermatology San Gallicano Dermatology Institute for Research and Care Rome Italy

[13 ]Department of Internal Medicine Respiratory Disease Clinic IRCCS Humanitas Clinical and Research Center Humanitas University Milan Italy

[14 ]Department of Emergency and Organ Transplantation School of Allergology and Clinical Immunology University of Bari Aldo Moro Bari Italy

[15 ]Ambulatorio di Allergologia Clinica San Carlo Paderno Dugnano, Milan Italy

Article

DOI: 10.1111/jdv.15350

PubMed ID: 30451325

SO-VID: 4c0bc3f1-ba8a-4f5a-9e39-607e055658aa

License:

http://onlinelibrary.wiley.com/termsAndConditions#vor

http://doi.wiley.com/10.1002/tdm_license_1.1

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