Usutu virus infection in a patient who underwent orthotropic liver transplantation, Italy, August-September 2009

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Abstract

We report a case of Usutu virus (USUV)-related illness in a patient that underwent an orthotropic liver transplant (OLT). Post transplant, the patient developed clinical signs of a possible neuroinvasive disease with a significant loss of cerebral functions. USUV was isolated in Vero E6 cells from a plasma sample obtained immediately before the surgery, and USUV RNA was demonstrated by RT-PCR and sequencing. This report enlarges the panel of emerging mosquito-borne flavivirus-related disease in humans.

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Journal

Title: Eurosurveillance

Publisher: European Centre for Disease Control and Prevention (ECDC)

ISSN (Print): 1560-7917

Publication date Created: December 17 2009

Publication date (Print): December 17 2009

Volume: 14

Issue: 50

Affiliations

[1 ] These Authors contributed equally to this paper and are listed in alphabetical order

[2 ]Clinical Microbiology Unit, Regional Reference Centre for Microbiological Emergencies – CRREM, St. Orsola-Malpighi University Hospital, University of Bologna, Bologna, Italy

[3 ]Oncology and Haematology Unit, Modena University Hospital, Modena, Italy

[4 ]Experimental Institute for Animal Health and Protection of Lombardia and Emilia-Romagna, Brescia, Italy

[5 ]Liver and Multivisceral Transplant Center, University of Modena and Reggio Emilia, Modena, Italy

[6 ]Anaestesiology and Intensive Care Unit 1, Modena University Hospital, Modena, Italy

Article

DOI: 10.2807/ese.14.50.19448-en

PubMed ID: 20070935

SO-VID: 433755ad-6c29-4a01-a440-02ffa652dbaf

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