Marie N. N. Hellem:
ORCID: https://orcid.org/0000-0002-9026-1073
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
InvestigationRole: MethodologyRole: Project administrationRole: Writing – original
draftRole: Writing – review & editing
Tua Vinther-Jensen: Role: ConceptualizationRole: Data curationRole: Writing – original draftRole: Writing
– review & editing
Lasse Anderberg: Role: SoftwareRole: Writing – original draft
Esben Budtz-Jørgensen: Role: Data curationRole: Formal analysisRole: SupervisionRole: ValidationRole: Writing
– review & editing
Lena E. Hjermind: Role: Writing – review & editing
Vibeke Andrée Larsen: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: SupervisionRole:
Writing – review & editing
Jørgen E. Nielsen: Role: ConceptualizationRole: Data curationRole: Funding acquisitionRole: InvestigationRole:
MethodologyRole: Project administrationRole: ResourcesRole: SupervisionRole: Writing
– original draftRole: Writing – review & editing
Ian Law: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
MethodologyRole: Project administrationRole: SoftwareRole: SupervisionRole: Writing
– original draftRole: Writing – review & editing
Pedro Fernandez-Funez: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS One
Journal ID (publisher-id): plos
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
11
June
2021
Publication date Collection: 2021
Volume: 16
Issue: 6
Electronic Location Identifier: e0252683
Affiliations
[1
]
The Neurogenetics Clinic, Danish Dementia Research Centre, Rigshospitalet, University
of Copenhagen, Copenhagen, Denmark
[2
]
Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University
of Copenhagen, Copenhagen, Denmark
[3
]
Department of Public Health, Section of Biostatistics, University of Copenhagen, Copenhagen,
Denmark
[4
]
Department of Radiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
University of Minnesota Duluth, UNITED STATES
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-21-01102
DOI: 10.1371/journal.pone.0252683
PMC ID: 8195345
PubMed ID: 34115782
SO-VID: 4273f476-db40-453d-85c4-8a107da55f32
Copyright © © 2021 Hellem et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by:
Danish Huntington's disease association Research foundation
Award Recipient
:
ORCID: https://orcid.org/0000-0002-9026-1073
Marie N. N. Hellem
Funded by:
funder-id http://dx.doi.org/10.13039/501100005111, Rigshospitalet;
Award ID: the research board at Rigshospitalet
Award Recipient
:
ORCID: https://orcid.org/0000-0002-9026-1073
Marie N. N. Hellem
Funded by:
funder-id http://dx.doi.org/10.13039/501100009708, Novo Nordisk Fonden;
Award Recipient
:
Jørgen E. Nielsen
Funded by:
funder-id http://dx.doi.org/10.13039/501100006197, Fonden til Lægevidenskabens Fremme;
Award Recipient
:
ORCID: https://orcid.org/0000-0002-9026-1073
Marie N. N. Hellem
Funded by:
funder-id http://dx.doi.org/10.13039/501100010359, Læge Søren Segel og Hustru Johanne Wiibroe Segels Forskningsfond;
Award Recipient
:
ORCID: https://orcid.org/0000-0002-9026-1073
Marie N. N. Hellem
MNNH received funds from Danish Huntington's Disease Association Resaerch Foundation,
http://huntingtons.dk/. The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript. MNNH received funding from The Research
Board at Rigshospitalet,
https://www.rigshospitalet.dk/english/Pages/default.aspx. The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript. MNNH received funding from A.P. Møller
Foundation,
https://www.apmollerfonde.dk/om-fonden/. The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript. MNNH received funding from The Søren
Segel & Johanne Wiibro Segel’s Research Fund,
https://www.legatbogen.dk/lge-sren-segel-og-hustru-johanne-wiibroe-segel-forskningsfond. The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript. JEN received funding from The Novo Nordisk
Foundation,
https://novonordiskfonden.dk/en/. The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Diagnostic Medicine
Subject:
Diagnostic Radiology
Subject:
Magnetic Resonance Imaging
Subject:
Research and Analysis Methods
Subject:
Imaging Techniques
Subject:
Diagnostic Radiology
Subject:
Magnetic Resonance Imaging
Subject:
Medicine and Health Sciences
Subject:
Radiology and Imaging
Subject:
Diagnostic Radiology
Subject:
Magnetic Resonance Imaging
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Polymer Chemistry
Subject:
Macromolecules
Subject:
Polymers
Subject:
Polyvinyl Chloride
Subject:
Physical Sciences
Subject:
Materials Science
Subject:
Materials
Subject:
Polymers
Subject:
Polyvinyl Chloride
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Polymer Chemistry
Subject:
Polymers
Subject:
Polyvinyl Chloride
Subject:
Medicine and Health Sciences
Subject:
Medical Conditions
Subject:
Genetic Diseases
Subject:
Autosomal Dominant Diseases
Subject:
Huntington Disease
Subject:
Medicine and Health Sciences
Subject:
Clinical Genetics
Subject:
Genetic Diseases
Subject:
Autosomal Dominant Diseases
Subject:
Huntington Disease
Subject:
Medicine and Health Sciences
Subject:
Medical Conditions
Subject:
Neurodegenerative Diseases
Subject:
Huntington Disease
Subject:
Medicine and Health Sciences
Subject:
Neurology
Subject:
Neurodegenerative Diseases
Subject:
Huntington Disease
Subject:
Research and Analysis Methods
Subject:
Imaging Techniques
Subject:
Neuroimaging
Subject:
Positron Emission Tomography
Subject:
Biology and Life Sciences
Subject:
Neuroscience
Subject:
Neuroimaging
Subject:
Positron Emission Tomography
Subject:
Medicine and Health Sciences
Subject:
Diagnostic Medicine
Subject:
Diagnostic Radiology
Subject:
Tomography
Subject:
Positron Emission Tomography
Subject:
Research and Analysis Methods
Subject:
Imaging Techniques
Subject:
Diagnostic Radiology
Subject:
Tomography
Subject:
Positron Emission Tomography
Subject:
Medicine and Health Sciences
Subject:
Radiology and Imaging
Subject:
Diagnostic Radiology
Subject:
Tomography
Subject:
Positron Emission Tomography
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Metabolism
Subject:
Carbohydrate Metabolism
Subject:
Glucose Metabolism
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Brain
Subject:
Neostriatum
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Brain
Subject:
Neostriatum
Subject:
Medicine and Health Sciences
Subject:
Clinical Medicine
Subject:
Signs and Symptoms
Subject:
Atrophy
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Nervous System
Subject:
Central Nervous System
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Nervous System
Subject:
Central Nervous System
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