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      Exploring the digital footprint of depression: a PRISMA systematic literature review of the empirical evidence

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          Abstract

          Background

          This PRISMA systematic literature review examined the use of digital data collection methods (including ecological momentary assessment [EMA], experience sampling method [ESM], digital biomarkers, passive sensing, mobile sensing, ambulatory assessment, and time-series analysis), emphasizing on digital phenotyping (DP) to study depression. DP is defined as the use of digital data to profile health information objectively.

          Aims

          Four distinct yet interrelated goals underpin this study: (a) to identify empirical research examining the use of DP to study depression; (b) to describe the different methods and technology employed; (c) to integrate the evidence regarding the efficacy of digital data in the examination, diagnosis, and monitoring of depression and (d) to clarify DP definitions and digital mental health records terminology.

          Results

          Overall, 118 studies were assessed as eligible. Considering the terms employed, “EMA”, “ESM”, and “DP” were the most predominant. A variety of DP data sources were reported, including voice, language, keyboard typing kinematics, mobile phone calls and texts, geocoded activity, actigraphy sensor-related recordings (i.e., steps, sleep, circadian rhythm), and self-reported apps’ information. Reviewed studies employed subjectively and objectively recorded digital data in combination with interviews and psychometric scales.

          Conclusions

          Findings suggest links between a person’s digital records and depression. Future research recommendations include (a) deriving consensus regarding the DP definition and (b) expanding the literature to consider a person’s broader contextual and developmental circumstances in relation to their digital data/records.

          Supplementary Information

          The online version contains supplementary material available at 10.1186/s12888-022-04013-y.

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          Most cited references130

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          PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation

          Scoping reviews, a type of knowledge synthesis, follow a systematic approach to map evidence on a topic and identify main concepts, theories, sources, and knowledge gaps. Although more scoping reviews are being done, their methodological and reporting quality need improvement. This document presents the PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) checklist and explanation. The checklist was developed by a 24-member expert panel and 2 research leads following published guidance from the EQUATOR (Enhancing the QUAlity and Transparency Of health Research) Network. The final checklist contains 20 essential reporting items and 2 optional items. The authors provide a rationale and an example of good reporting for each item. The intent of the PRISMA-ScR is to help readers (including researchers, publishers, commissioners, policymakers, health care providers, guideline developers, and patients or consumers) develop a greater understanding of relevant terminology, core concepts, and key items to report for scoping reviews.
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            The PHQ-9: validity of a brief depression severity measure.

            While considerable attention has focused on improving the detection of depression, assessment of severity is also important in guiding treatment decisions. Therefore, we examined the validity of a brief, new measure of depression severity. The Patient Health Questionnaire (PHQ) is a self-administered version of the PRIME-MD diagnostic instrument for common mental disorders. The PHQ-9 is the depression module, which scores each of the 9 DSM-IV criteria as "0" (not at all) to "3" (nearly every day). The PHQ-9 was completed by 6,000 patients in 8 primary care clinics and 7 obstetrics-gynecology clinics. Construct validity was assessed using the 20-item Short-Form General Health Survey, self-reported sick days and clinic visits, and symptom-related difficulty. Criterion validity was assessed against an independent structured mental health professional (MHP) interview in a sample of 580 patients. As PHQ-9 depression severity increased, there was a substantial decrease in functional status on all 6 SF-20 subscales. Also, symptom-related difficulty, sick days, and health care utilization increased. Using the MHP reinterview as the criterion standard, a PHQ-9 score > or =10 had a sensitivity of 88% and a specificity of 88% for major depression. PHQ-9 scores of 5, 10, 15, and 20 represented mild, moderate, moderately severe, and severe depression, respectively. Results were similar in the primary care and obstetrics-gynecology samples. In addition to making criteria-based diagnoses of depressive disorders, the PHQ-9 is also a reliable and valid measure of depression severity. These characteristics plus its brevity make the PHQ-9 a useful clinical and research tool.
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              The CES-D Scale: A Self-Report Depression Scale for Research in the General Population

              L Radloff (1977)
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                Author and article information

                Contributors
                Daniel.zarate@live.vu.edu.au
                Journal
                BMC Psychiatry
                BMC Psychiatry
                BMC Psychiatry
                BioMed Central (London )
                1471-244X
                22 June 2022
                22 June 2022
                2022
                : 22
                : 421
                Affiliations
                [1 ]GRID grid.1019.9, ISNI 0000 0001 0396 9544, Institute for Health and Sport, Victoria University, ; Melbourne, Australia
                [2 ]GRID grid.5216.0, ISNI 0000 0001 2155 0800, Department of Psychology, , University of Athens, ; Athens, Greece
                [3 ]GRID grid.254880.3, ISNI 0000 0001 2179 2404, Center for Technology and Behavioral Health, Geisel School of Medicine, , Dartmouth College, ; Hanover, USA
                [4 ]GRID grid.254880.3, ISNI 0000 0001 2179 2404, Department of Biomedical Data Science, , Geisel School of Medicine, Dartmouth College, ; Hanover, USA
                [5 ]GRID grid.254880.3, ISNI 0000 0001 2179 2404, Department of Psychiatry, Geisel School of Medicine, , Dartmouth College, ; Hanover, USA
                [6 ]GRID grid.254880.3, ISNI 0000 0001 2179 2404, Quantitative Biomedical Sciences Program, , Dartmouth College, ; Hanover, USA
                Article
                4013
                10.1186/s12888-022-04013-y
                9214685
                35733121
                41ba71cf-4ef0-49d9-8a28-5f53afe4560d
                © The Author(s) 2022

                Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

                History
                : 20 July 2021
                : 17 May 2022
                Funding
                Funded by: Victoria University
                Categories
                Research
                Custom metadata
                © The Author(s) 2022

                Clinical Psychology & Psychiatry
                digital phenotype,ecological momentary assessment,experience sampling,passive sensing,ambulatory assessment,depression,prisma,systematic literature review

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